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Imaging Protocol and Criteria for Evaluation of Axillary Lymph Nodes in the NAUTILUS Trial
Axillary ultrasonography (US) is the most commonly used imaging modality for nodal evaluation in patients with breast cancer. No Axillary Surgical Treatment in Clinically Lymph Node-Negative Patients after Ultrasonography (NAUTILUS) is a prospective, multicenter, randomized controlled trial investig...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Breast Cancer Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724375/ https://www.ncbi.nlm.nih.gov/pubmed/34877830 http://dx.doi.org/10.4048/jbc.2021.24.e47 |
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author | Chang, Jung Min Shin, Hee Jung Choi, Ji Soo Shin, Sung Ui Choi, Bo Hwa Kim, Min Jung Yoon, Jung Hyun Chung, Jin Kim, Tae Hee Han, Boo-Kyung Kim, Hak Hee Moon, Woo Kyung |
author_facet | Chang, Jung Min Shin, Hee Jung Choi, Ji Soo Shin, Sung Ui Choi, Bo Hwa Kim, Min Jung Yoon, Jung Hyun Chung, Jin Kim, Tae Hee Han, Boo-Kyung Kim, Hak Hee Moon, Woo Kyung |
author_sort | Chang, Jung Min |
collection | PubMed |
description | Axillary ultrasonography (US) is the most commonly used imaging modality for nodal evaluation in patients with breast cancer. No Axillary Surgical Treatment in Clinically Lymph Node-Negative Patients after Ultrasonography (NAUTILUS) is a prospective, multicenter, randomized controlled trial investigating whether sentinel lymph node biopsy (SLNB) can be safely omitted in patients with clinically and sonographically node-negative T1–2 breast cancer treated with breast-conserving therapy. In this trial, a standardized imaging protocol and criteria were established for the evaluation of axillary lymph nodes. Women lacking palpable lymph nodes underwent axillary US to dismiss suspicious nodal involvement. Patients with a round hypoechoic node with effaced hilum or indistinct margins were excluded. Patients with T1 tumors and a single node with a cortical thickness ≥ 3 mm underwent US-guided biopsy. Finally, patients with negative axillary US findings were included. The NAUTILUS axillary US nodal assessment criteria facilitate the proper selection of candidates who can omit SLNB. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT04303715 |
format | Online Article Text |
id | pubmed-8724375 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Korean Breast Cancer Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-87243752022-01-12 Imaging Protocol and Criteria for Evaluation of Axillary Lymph Nodes in the NAUTILUS Trial Chang, Jung Min Shin, Hee Jung Choi, Ji Soo Shin, Sung Ui Choi, Bo Hwa Kim, Min Jung Yoon, Jung Hyun Chung, Jin Kim, Tae Hee Han, Boo-Kyung Kim, Hak Hee Moon, Woo Kyung J Breast Cancer Brief Communication Axillary ultrasonography (US) is the most commonly used imaging modality for nodal evaluation in patients with breast cancer. No Axillary Surgical Treatment in Clinically Lymph Node-Negative Patients after Ultrasonography (NAUTILUS) is a prospective, multicenter, randomized controlled trial investigating whether sentinel lymph node biopsy (SLNB) can be safely omitted in patients with clinically and sonographically node-negative T1–2 breast cancer treated with breast-conserving therapy. In this trial, a standardized imaging protocol and criteria were established for the evaluation of axillary lymph nodes. Women lacking palpable lymph nodes underwent axillary US to dismiss suspicious nodal involvement. Patients with a round hypoechoic node with effaced hilum or indistinct margins were excluded. Patients with T1 tumors and a single node with a cortical thickness ≥ 3 mm underwent US-guided biopsy. Finally, patients with negative axillary US findings were included. The NAUTILUS axillary US nodal assessment criteria facilitate the proper selection of candidates who can omit SLNB. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT04303715 Korean Breast Cancer Society 2021-11-24 /pmc/articles/PMC8724375/ /pubmed/34877830 http://dx.doi.org/10.4048/jbc.2021.24.e47 Text en © 2021 Korean Breast Cancer Society https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Brief Communication Chang, Jung Min Shin, Hee Jung Choi, Ji Soo Shin, Sung Ui Choi, Bo Hwa Kim, Min Jung Yoon, Jung Hyun Chung, Jin Kim, Tae Hee Han, Boo-Kyung Kim, Hak Hee Moon, Woo Kyung Imaging Protocol and Criteria for Evaluation of Axillary Lymph Nodes in the NAUTILUS Trial |
title | Imaging Protocol and Criteria for Evaluation of Axillary Lymph Nodes in the NAUTILUS Trial |
title_full | Imaging Protocol and Criteria for Evaluation of Axillary Lymph Nodes in the NAUTILUS Trial |
title_fullStr | Imaging Protocol and Criteria for Evaluation of Axillary Lymph Nodes in the NAUTILUS Trial |
title_full_unstemmed | Imaging Protocol and Criteria for Evaluation of Axillary Lymph Nodes in the NAUTILUS Trial |
title_short | Imaging Protocol and Criteria for Evaluation of Axillary Lymph Nodes in the NAUTILUS Trial |
title_sort | imaging protocol and criteria for evaluation of axillary lymph nodes in the nautilus trial |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724375/ https://www.ncbi.nlm.nih.gov/pubmed/34877830 http://dx.doi.org/10.4048/jbc.2021.24.e47 |
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