Helical inchworming: a novel translocation mechanism for a ring ATPase

Ring ATPases perform a variety of tasks in the cell. Their function involves complex communication and coordination among the often identical subunits. Translocases in this group are of particular interest as they involve both chemical and mechanical actions in their operation. We study the DNA pack...

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Detalles Bibliográficos
Autores principales: Tong, Alexander B., Bustamante, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724481/
https://www.ncbi.nlm.nih.gov/pubmed/35047087
http://dx.doi.org/10.1007/s12551-021-00883-w
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author Tong, Alexander B.
Bustamante, Carlos
author_facet Tong, Alexander B.
Bustamante, Carlos
author_sort Tong, Alexander B.
collection PubMed
description Ring ATPases perform a variety of tasks in the cell. Their function involves complex communication and coordination among the often identical subunits. Translocases in this group are of particular interest as they involve both chemical and mechanical actions in their operation. We study the DNA packaging motor of bacteriophage φ29, and using single-molecule optical tweezers and single-particle cryo-electron microscopy, have discovered a novel translocation mechanism for a molecular motor.
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spelling pubmed-87244812022-01-18 Helical inchworming: a novel translocation mechanism for a ring ATPase Tong, Alexander B. Bustamante, Carlos Biophys Rev Commentary Ring ATPases perform a variety of tasks in the cell. Their function involves complex communication and coordination among the often identical subunits. Translocases in this group are of particular interest as they involve both chemical and mechanical actions in their operation. We study the DNA packaging motor of bacteriophage φ29, and using single-molecule optical tweezers and single-particle cryo-electron microscopy, have discovered a novel translocation mechanism for a molecular motor. Springer Berlin Heidelberg 2021-11-24 /pmc/articles/PMC8724481/ /pubmed/35047087 http://dx.doi.org/10.1007/s12551-021-00883-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Commentary
Tong, Alexander B.
Bustamante, Carlos
Helical inchworming: a novel translocation mechanism for a ring ATPase
title Helical inchworming: a novel translocation mechanism for a ring ATPase
title_full Helical inchworming: a novel translocation mechanism for a ring ATPase
title_fullStr Helical inchworming: a novel translocation mechanism for a ring ATPase
title_full_unstemmed Helical inchworming: a novel translocation mechanism for a ring ATPase
title_short Helical inchworming: a novel translocation mechanism for a ring ATPase
title_sort helical inchworming: a novel translocation mechanism for a ring atpase
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724481/
https://www.ncbi.nlm.nih.gov/pubmed/35047087
http://dx.doi.org/10.1007/s12551-021-00883-w
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