Cargando…

Association of the Polygenic Risk Score With the Probability of Prodromal Parkinson’s Disease in Older Adults

Several studies have investigated the association of the Parkinson’s disease (PD) polygenic risk score (PRS) with several aspects of well-established PD. We sought to evaluate the association of PRS with the prodromal stage of PD. We calculated PRS in a longitudinal sample (n = 1120) of community dw...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maraki, Maria I., Hatzimanolis, Alexandros, Mourtzi, Niki, Stefanis, Leonidas, Yannakoulia, Mary, Kosmidis, Mary H., Dardiotis, Efthimios, Hadjigeorgiou, Georgios M., Sakka, Paraskevi, Ramirez, Alfredo, Grenier-Boley, Benjamin, Lambert, Jean-Charles, Heilmann-Heimbach, Stefanie, Stamelou, Maria, Scarmeas, Nikolaos, Xiromerisiou, Georgia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724535/ https://www.ncbi.nlm.nih.gov/pubmed/34992521 http://dx.doi.org/10.3389/fnmol.2021.739571

Ejemplares similares

Sleep Polygenic Risk Score Is Associated with Cognitive Changes over Time
por: Tsapanou, Angeliki, et al.
Publicado: (2021)

Vascular burden and genetic risk in association with cognitive performance and dementia in a population-based study
por: Georgakis, Marios K., et al.
Publicado: (2022)

The Association of Adherence to the Mediterranean Diet with Depression in Older Adults Longitudinally Taking into Account Cognitive Status: Results from the HELIAD Study
por: Mamalaki, Eirini, et al.
Publicado: (2023)

Cognitive trajectories preluding the imminent onset of Alzheimer’s disease dementia in individuals with normal cognition: results from the HELIAD cohort
por: Liampas, Ioannis, et al.
Publicado: (2022)

Longitudinal Examination of Body Mass Index and Cognitive Function in Older Adults: The HELIAD Study
por: Grapsa, Ismini, et al.
Publicado: (2023)

Qualitative Verbal Fluency Components as Prognostic Factors for Developing Alzheimer’s Dementia and Mild Cognitive Impairment: Results from the Population-Based HELIAD Cohort
por: Liampas, Ioannis, et al.
Publicado: (2022)

Language Differences Among Individuals with Normal Cognition, Amnestic and Non-Amnestic MCI, and Alzheimer’s Disease
por: Liampas, Ioannis, et al.
Publicado: (2022)

Mediterranean diet and cognitive health: Initial results from the Hellenic Longitudinal Investigation of Ageing and Diet
por: Anastasiou, Costas A., et al.
Publicado: (2017)

Mediterranean Lifestyle in Relation to Cognitive Health: Results from the HELIAD Study
por: Anastasiou, Costas A., et al.
Publicado: (2018)

Exploring Verbal Fluency Strategies among Individuals with Normal Cognition, Amnestic and Non-Amnestic Mild Cognitive Impairment, and Alzheimer’s Disease
por: Bairami, Styliani, et al.
Publicado: (2023)

The Longitudinal Association of Lifestyle with Cognitive Health and Dementia Risk: Findings from the HELIAD Study
por: Mamalaki, Eirini, et al.
Publicado: (2022)

Dataset on the associations between sleep quality/duration and cognitive performance in cognitively healthy older adults
por: Tsapanou, A., et al.
Publicado: (2017)

Organochlorine pesticide levels in Greek patients with Parkinson’s disease
por: Dardiotis, Efthimios, et al.
Publicado: (2020)

Neurodegeneration and Inflammation—An Interesting Interplay in Parkinson’s Disease
por: Marogianni, Chrysoula, et al.
Publicado: (2020)

S125. THE ROLE OF DUP, DUI AND POLYGENIC SCORE FOR SCHIZOPHRENIA ON COGNITION IN ATHENS FEP STUDY SAMPLE
por: Dimitrakopoulos, Stefanos, et al.
Publicado: (2020)

Population Attributable Fractions for Modifiable Risk Factors of Incident Dementia in Cognitively Normal and Mild Cognitively Impaired Older Adults: Data from Two Cohort Studies
por: Wezeman, Sandra L., et al.
Publicado: (2022)

THAP1 Mutations and Dystonia Phenotypes: Genotype Phenotype Correlations
por: Xiromerisiou, Georgia, et al.
Publicado: (2012)

Common genetic variation and schizophrenia polygenic risk influence neurocognitive performance in young adulthood
por: Hatzimanolis, Alex, et al.
Publicado: (2015)

Screening for the C9ORF72 expansion in Greek Huntington Disease phenocopies and controls and meta-analysis of current data
por: Rikos, Dimitrios, et al.
Publicado: (2020)

Serum Uric Acid as a Putative Biomarker in Prodromal Parkinson’s Disease: Longitudinal Data from the PPMI Study
por: Koros, Christos, et al.
Publicado: (2023)

Weight Loss Maintenance: Have We Missed the Brain?
por: Poulimeneas, Dimitrios, et al.
Publicado: (2018)

Association of Cognitive Polygenic Index and Cognitive Performance with Age in Cognitively Healthy Adults
por: Tsapanou, Angeliki, et al.
Publicado: (2023)

Dietary and Nutrient Patterns and Brain MRI Biomarkers in Dementia-Free Adults
por: Drouka, Archontoula, et al.
Publicado: (2022)

Polygenic indices for cognition in healthy aging; the role of brain measures
por: Tsapanou, A., et al.
Publicado: (2023)

Personality Traits and Weight Loss Maintenance: A Cross-Sectional Study
por: Koutras, Yiannis, et al.
Publicado: (2021)

Precision Medicine and Global Health: The Good, the Bad, and the Ugly
por: Mentis, Alexios-Fotios A., et al.
Publicado: (2018)

Corrigendum: Precision Medicine and Global Health: The Good, the Bad, and the Ugly
por: Mentis, Alexios-Fotios A., et al.
Publicado: (2018)

Reporting Quality of Randomized Controlled Trials in Restless Legs Syndrome Based on the CONSORT Statement
por: Rikos, Dimitrios, et al.
Publicado: (2019)

Cognitive Impairment in Heart Failure
por: Dardiotis, Efthimios, et al.
Publicado: (2012)

Genetic polymorphisms of FAS and EVER genes in a Greek population and their susceptibility to cervical cancer: a case control study
por: Pavlidou, Evangelia, et al.
Publicado: (2016)

Genetic Risk Factors for Essential Tremor: A Review
por: Siokas, Vasileios, et al.
Publicado: (2020)

Evaluation of MMP1 and MMP3 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma
por: Tsironi, Evangelia E., et al.
Publicado: (2009)

Genetic variations in the SULF1 gene alter the risk of cervical cancer and precancerous lesions
por: Dardiotis, Efthimios, et al.
Publicado: (2018)

Peripheral Inflammatory Markers TNF-α and CCL2 Revisited: Association with Parkinson’s Disease Severity
por: Xiromerisiou, Georgia, et al.
Publicado: (2022)

Cognitive Neurorehabilitation in Acquired Neurological Brain Injury
por: Messinis, Lambros, et al.
Publicado: (2019)

Acute Schmorl's Node during Strenuous Monofin Swimming: A Case Report and Review of the Literature
por: Paterakis, Konstantinos N., et al.
Publicado: (2012)

Objective Physical Function in the Alzheimer’s Disease Continuum: Association with Cerebrospinal Fluid Biomarkers in the ALBION Study
por: Sampatakakis, Stefanos N., et al.
Publicado: (2023)

Non-Verbal and Verbal Fluency in Prodromal Huntington's Disease
por: Robins Wahlin, Tarja-Brita, et al.
Publicado: (2015)

Polygenic risk for obsessive-compulsive disorder (OCD) predicts brain response during working memory task in OCD, unaffected relatives, and healthy controls
por: Heinzel, Stephan, et al.
Publicado: (2021)

Lack of evidence for a genetic association between FGF20 and Parkinson's disease in Finnish and Greek patients
por: Clarimon, Jordi, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_tp1upesigasnt9pkc6v27ec7l4