Sensitive Immunopeptidomics by Leveraging Available Large-Scale Multi-HLA Spectral Libraries, Data-Independent Acquisition, and MS/MS Prediction

Mass spectrometry (MS) is the state-of-the-art methodology for capturing the breadth and depth of the immunopeptidome across human leukocyte antigen (HLA) allotypes and cell types. The majority of studies in the immunopeptidomics field are discovery driven. Hence, data-dependent tandem MS (MS/MS) ac...

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Detalles Bibliográficos
Autores principales: Pak, HuiSong, Michaux, Justine, Huber, Florian, Chong, Chloe, Stevenson, Brian J., Müller, Markus, Coukos, George, Bassani-Sternberg, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Technological Innovation and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724634/
https://www.ncbi.nlm.nih.gov/pubmed/33845167
http://dx.doi.org/10.1016/j.mcpro.2021.100080

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