USP10 regulates B cell response to SARS-CoV-2 or HIV-1 nanoparticle vaccines through deubiquitinating AID

Activation-induced cytidine deaminase (AID) initiates class-switch recombination and somatic hypermutation (SHM) in antibody genes. Protein expression and activity are tightly controlled by various mechanisms. However, it remains unknown whether a signal from the extracellular environment directly a...

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Detalles Bibliográficos
Autores principales: Luo, Yuewen, Zhang, Xiantao, Chen, Ran, Li, Rong, Liu, Yang, Zhang, Junsong, liu, Qin, Si, Meijun, Liu, Jun, Wu, Bolin, Wang, Xuemei, Wu, Shijian, Zhang, Yiwen, Zhang, Xu, Guo, Deyin, He, Xin, Pan, Ting, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724756/
https://www.ncbi.nlm.nih.gov/pubmed/34983926
http://dx.doi.org/10.1038/s41392-021-00858-z

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