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Immunopeptidogenomics: Harnessing RNA-Seq to Illuminate the Dark Immunopeptidome

Human leukocyte antigen (HLA) molecules are cell-surface glycoproteins that present peptide antigens on the cell surface for surveillance by T lymphocytes, which contemporaneously seek signs of disease. Mass spectrometric analysis allows us to identify large numbers of these peptides (the immunopept...

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Detalles Bibliográficos
Autores principales: Scull, Katherine E., Pandey, Kirti, Ramarathinam, Sri H., Purcell, Anthony W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724885/
https://www.ncbi.nlm.nih.gov/pubmed/34509645
http://dx.doi.org/10.1016/j.mcpro.2021.100143