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Recombinant Human Proteoglycan 4 Regulates Phagocytic Activation of Monocytes and Reduces IL-1β Secretion by Urate Crystal Stimulated Gout PBMCs

OBJECTIVES: To compare phagocytic activities of monocytes in peripheral blood mononuclear cells (PBMCs) from acute gout patients and normal subjects, examine monosodium urate monohydrate (MSU) crystal-induced IL-1β secretion ± recombinant human proteoglycan 4 (rhPRG4) or interleukin-1 receptor antag...

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Detalles Bibliográficos
Autores principales: ElSayed, Sandy, Jay, Gregory D., Cabezas, Ralph, Qadri, Marwa, Schmidt, Tannin A., Elsaid, Khaled A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725049/
https://www.ncbi.nlm.nih.gov/pubmed/34992596
http://dx.doi.org/10.3389/fimmu.2021.771677