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CRISPR screens uncover protective effect of PSTK as a regulator of chemotherapy-induced ferroptosis in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is among the most common forms of cancer and is associated with poor patient outcomes. The emergence of therapeutic resistance has hampered the efficacy of targeted treatments employed to treat HCC patients to date. In this study, we conducted a series of C...

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Detalles Bibliográficos
Autores principales:	Chen, Yiran, Li, Li, Lan, Jie, Cui, Yang, Rao, Xiaosong, Zhao, Jing, Xing, Tao, Ju, Gaoda, Song, Guangtao, Lou, Jizhong, Liang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725338/ https://www.ncbi.nlm.nih.gov/pubmed/34983546 http://dx.doi.org/10.1186/s12943-021-01466-9

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