Application value of the treatment of breast cancer bone metastases with radioactive seed 125I implantation under CT-guidance

BACKGROUND: To investigate the application value of the treatment of breast cancer bone metastases with radioactive seed 125I implantation under CT-guidance. METHODS: A total of 90 patients with breast cancer admitted to our hospital from January 2017 to January 2018 were selected as the research ob...

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Autores principales: Li, Haiwen, Wang, Maobo, Zhu, Zhenhua, Lu, Yingqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725351/
https://www.ncbi.nlm.nih.gov/pubmed/34983423
http://dx.doi.org/10.1186/s12880-021-00726-w
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author Li, Haiwen
Wang, Maobo
Zhu, Zhenhua
Lu, Yingqiang
author_facet Li, Haiwen
Wang, Maobo
Zhu, Zhenhua
Lu, Yingqiang
author_sort Li, Haiwen
collection PubMed
description BACKGROUND: To investigate the application value of the treatment of breast cancer bone metastases with radioactive seed 125I implantation under CT-guidance. METHODS: A total of 90 patients with breast cancer admitted to our hospital from January 2017 to January 2018 were selected as the research objects and were divided into control group and experimental group according to random grouping, with 45 cases in each group. Conventional treatment was used in the control group, while the treatment of radioactive seed 125I implantation under CT-guidance was used in the experimental group. The clinical efficacy, pain intensity and levels of carcinoembryonic antigen (CEA), carcinoembryonic antigen 153 (CA153), carbohydrate antigen (CA125) in the two groups were compared. RESULTS: As for the pain intensity, it was evidently lower in the experimental group after treatment than that in the control group (P < 0.05); as for the total effective rate, it was obviously higher in the experimental group after treatment than that in the control group (P < 0.05); as for the levels of CEA, CA153 and CA125, the data in the experimental group after treatment were much lower than the control group (P < 0.05). CONCLUSION: Radioactive seed 125I implantation under CT-guidance can effectively improve the effect of the treatment of breast cancer bone metastases. It has curative efficacy and it is worth promoting and using.
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spelling pubmed-87253512022-01-06 Application value of the treatment of breast cancer bone metastases with radioactive seed 125I implantation under CT-guidance Li, Haiwen Wang, Maobo Zhu, Zhenhua Lu, Yingqiang BMC Med Imaging Research BACKGROUND: To investigate the application value of the treatment of breast cancer bone metastases with radioactive seed 125I implantation under CT-guidance. METHODS: A total of 90 patients with breast cancer admitted to our hospital from January 2017 to January 2018 were selected as the research objects and were divided into control group and experimental group according to random grouping, with 45 cases in each group. Conventional treatment was used in the control group, while the treatment of radioactive seed 125I implantation under CT-guidance was used in the experimental group. The clinical efficacy, pain intensity and levels of carcinoembryonic antigen (CEA), carcinoembryonic antigen 153 (CA153), carbohydrate antigen (CA125) in the two groups were compared. RESULTS: As for the pain intensity, it was evidently lower in the experimental group after treatment than that in the control group (P < 0.05); as for the total effective rate, it was obviously higher in the experimental group after treatment than that in the control group (P < 0.05); as for the levels of CEA, CA153 and CA125, the data in the experimental group after treatment were much lower than the control group (P < 0.05). CONCLUSION: Radioactive seed 125I implantation under CT-guidance can effectively improve the effect of the treatment of breast cancer bone metastases. It has curative efficacy and it is worth promoting and using. BioMed Central 2022-01-04 /pmc/articles/PMC8725351/ /pubmed/34983423 http://dx.doi.org/10.1186/s12880-021-00726-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Li, Haiwen
Wang, Maobo
Zhu, Zhenhua
Lu, Yingqiang
Application value of the treatment of breast cancer bone metastases with radioactive seed 125I implantation under CT-guidance
title Application value of the treatment of breast cancer bone metastases with radioactive seed 125I implantation under CT-guidance
title_full Application value of the treatment of breast cancer bone metastases with radioactive seed 125I implantation under CT-guidance
title_fullStr Application value of the treatment of breast cancer bone metastases with radioactive seed 125I implantation under CT-guidance
title_full_unstemmed Application value of the treatment of breast cancer bone metastases with radioactive seed 125I implantation under CT-guidance
title_short Application value of the treatment of breast cancer bone metastases with radioactive seed 125I implantation under CT-guidance
title_sort application value of the treatment of breast cancer bone metastases with radioactive seed 125i implantation under ct-guidance
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725351/
https://www.ncbi.nlm.nih.gov/pubmed/34983423
http://dx.doi.org/10.1186/s12880-021-00726-w
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