Drug delivery of 6-bromoindirubin-3’-glycerol-oxime ether employing poly(d,l-lactide-co-glycolide)-based nanoencapsulation techniques with sustainable solvents

BACKGROUND: Insufficient solubility and stability of bioactive small molecules as well as poor biocompatibility may cause low bioavailability and are common obstacles in drug development. One example of such problematic molecules is 6-bromoindirubin-3'-glycerol-oxime ether (6BIGOE), a hydrophob...

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Detalles Bibliográficos
Autores principales: Czapka, Anna, Grune, Christian, Schädel, Patrick, Bachmann, Vivien, Scheuer, Karl, Dirauf, Michael, Weber, Christine, Skaltsounis, Alexios-Leandros, Jandt, Klaus D., Schubert, Ulrich S., Fischer, Dagmar, Werz, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725458/
https://www.ncbi.nlm.nih.gov/pubmed/34983538
http://dx.doi.org/10.1186/s12951-021-01179-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725458/
https://www.ncbi.nlm.nih.gov/pubmed/34983538
http://dx.doi.org/10.1186/s12951-021-01179-7

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