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Deformation of the nucleus by TGFβ1 via the remodeling of nuclear envelope and histone isoforms

The cause of nuclear shape abnormalities which are often seen in pre-neoplastic and malignant tissues is not clear. In this study we report that deformation of the nucleus can be induced by TGFβ1 stimulation in several cell lines including Huh7. In our results, the upregulated histone H3.3 expressio...

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Detalles Bibliográficos
Autores principales:	Chi, Ya-Hui, Wang, Wan-Ping, Hung, Ming-Chun, Liou, Gunn-Guang, Wang, Jing-Ya, Chao, Pen-Hsiu Grace
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725468/ https://www.ncbi.nlm.nih.gov/pubmed/34983624 http://dx.doi.org/10.1186/s13072-021-00434-3

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