Polymorphism of MMP-3 gene and imbalance expression of MMP-3 / TIMP-1 in articular cartilage are associated with an endemic osteochondropathy, Kashin- Beck disease

BACKGROUND: The etiology of Kashin-Beck disease (KBD), an endemic osteochondropathy, is largely unknown. Matrix metalloproteinase-3 (MMP-3) plays a central role in the initiation and progression of cartilage destruction, however, no study has reported on the relationship between KBD and MMP-3. The o...

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Detalles Bibliográficos
Autores principales: Shi, Bohui, Guo, Xiong, Iv, Aili, Zhang, Zengtie, Shi, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725486/
https://www.ncbi.nlm.nih.gov/pubmed/34980041
http://dx.doi.org/10.1186/s12891-021-04952-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725486/
https://www.ncbi.nlm.nih.gov/pubmed/34980041
http://dx.doi.org/10.1186/s12891-021-04952-9

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