Genome-wide association studies for growth traits in broilers

BACKGROUND: The identification of markers and genes for growth traits may not only benefit for marker assist selection /genomic selection but also provide important information for understanding the genetic foundation of growth traits in broilers. RESULTS: In the current study, we estimated the gene...

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Autores principales: Dou, Dachang, Shen, Linyong, Zhou, Jiamei, Cao, Zhiping, Luan, Peng, Li, Yumao, Xiao, Fan, Guo, Huaishun, Li, Hui, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725492/
https://www.ncbi.nlm.nih.gov/pubmed/34979907
http://dx.doi.org/10.1186/s12863-021-01017-7
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author Dou, Dachang
Shen, Linyong
Zhou, Jiamei
Cao, Zhiping
Luan, Peng
Li, Yumao
Xiao, Fan
Guo, Huaishun
Li, Hui
Zhang, Hui
author_facet Dou, Dachang
Shen, Linyong
Zhou, Jiamei
Cao, Zhiping
Luan, Peng
Li, Yumao
Xiao, Fan
Guo, Huaishun
Li, Hui
Zhang, Hui
author_sort Dou, Dachang
collection PubMed
description BACKGROUND: The identification of markers and genes for growth traits may not only benefit for marker assist selection /genomic selection but also provide important information for understanding the genetic foundation of growth traits in broilers. RESULTS: In the current study, we estimated the genetic parameters of eight growth traits in broilers and carried out the genome-wide association studies for these growth traits. A total of 113 QTNs discovered by multiple methods together, and some genes, including ACTA1, IGF2BP1, TAPT1, LDB2, PRKCA, TGFBR2, GLI3, SLC16A7, INHBA, BAMBI, APCDD1, GPR39, and GATA4, were identified as important candidate genes for rapid growth in broilers. CONCLUSIONS: The results of this study will provide important information for understanding the genetic foundation of growth traits in broilers. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12863-021-01017-7.
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spelling pubmed-87254922022-01-06 Genome-wide association studies for growth traits in broilers Dou, Dachang Shen, Linyong Zhou, Jiamei Cao, Zhiping Luan, Peng Li, Yumao Xiao, Fan Guo, Huaishun Li, Hui Zhang, Hui BMC Genom Data Research BACKGROUND: The identification of markers and genes for growth traits may not only benefit for marker assist selection /genomic selection but also provide important information for understanding the genetic foundation of growth traits in broilers. RESULTS: In the current study, we estimated the genetic parameters of eight growth traits in broilers and carried out the genome-wide association studies for these growth traits. A total of 113 QTNs discovered by multiple methods together, and some genes, including ACTA1, IGF2BP1, TAPT1, LDB2, PRKCA, TGFBR2, GLI3, SLC16A7, INHBA, BAMBI, APCDD1, GPR39, and GATA4, were identified as important candidate genes for rapid growth in broilers. CONCLUSIONS: The results of this study will provide important information for understanding the genetic foundation of growth traits in broilers. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12863-021-01017-7. BioMed Central 2022-01-03 /pmc/articles/PMC8725492/ /pubmed/34979907 http://dx.doi.org/10.1186/s12863-021-01017-7 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Dou, Dachang
Shen, Linyong
Zhou, Jiamei
Cao, Zhiping
Luan, Peng
Li, Yumao
Xiao, Fan
Guo, Huaishun
Li, Hui
Zhang, Hui
Genome-wide association studies for growth traits in broilers
title Genome-wide association studies for growth traits in broilers
title_full Genome-wide association studies for growth traits in broilers
title_fullStr Genome-wide association studies for growth traits in broilers
title_full_unstemmed Genome-wide association studies for growth traits in broilers
title_short Genome-wide association studies for growth traits in broilers
title_sort genome-wide association studies for growth traits in broilers
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725492/
https://www.ncbi.nlm.nih.gov/pubmed/34979907
http://dx.doi.org/10.1186/s12863-021-01017-7
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