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LncRNA HCG18 upregulates TRAF4/TRAF5 to facilitate proliferation, migration and EMT of epithelial ovarian cancer by targeting miR-29a/b

BACKGROUND: Although long noncoding RNA HLA complex group 18 (lncRNA HCG18) has been suggested to regulate cell growth in several tumours, the function of HCG18 in epithelial ovarian cancer (EOC) and its mechanism are still unclear. METHODS: shRNAs were applied to reduce HCG18 and related genes. For...

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Detalles Bibliográficos
Autores principales: Zhang, Fan, Luo, Bai-Hua, Wu, Qi-Hui, Li, Qing-Ling, Yang, Ke-Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725507/
https://www.ncbi.nlm.nih.gov/pubmed/34983361
http://dx.doi.org/10.1186/s10020-021-00415-y