Epigenetic biomarkers of ageing are predictive of mortality risk in a longitudinal clinical cohort of individuals diagnosed with oropharyngeal cancer

BACKGROUND: Epigenetic clocks are biomarkers of ageing derived from DNA methylation levels at a subset of CpG sites. The difference between age predicted by these clocks and chronological age, termed “epigenetic age acceleration”, has been shown to predict age-related disease and mortality. We aimed...

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Detalles Bibliográficos
Autores principales: Beynon, Rhona A., Ingle, Suzanne M., Langdon, Ryan, May, Margaret, Ness, Andy, Martin, Richard M., Suderman, Matthew, Ingarfield, Kate, Marioni, Riccardo E., McCartney, Daniel L., Waterboer, Tim, Pawlita, Michael, Relton, Caroline, Smith, George Davey, Richmond, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725548/
https://www.ncbi.nlm.nih.gov/pubmed/34980250
http://dx.doi.org/10.1186/s13148-021-01220-4

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