PixR, a Novel Activator of Conjugative Transfer of IncX4 Resistance Plasmids, Mitigates the Fitness Cost of mcr-1 Carriage in Escherichia coli

The emergence of the plasmid-borne colistin resistance gene mcr-1 threatens public health. IncX4-type plasmids are one of the most epidemiologically successful vehicles for spreading mcr-1 worldwide. Since MCR-1 is known for imposing a fitness cost to its host bacterium, the successful spread of mcr...

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Detalles Bibliográficos
Autores principales: Yi, Lingxian, Durand, Romain, Grenier, Frédéric, Yang, Jun, Yu, Kaiyang, Burrus, Vincent, Liu, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725589/
https://www.ncbi.nlm.nih.gov/pubmed/35089067
http://dx.doi.org/10.1128/mbio.03209-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725589/
https://www.ncbi.nlm.nih.gov/pubmed/35089067
http://dx.doi.org/10.1128/mbio.03209-21

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