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A Retrotranslocation Assay That Predicts Defective VCP/p97-Mediated Trafficking of a Retroviral Signal Peptide

Studies of viral replication have provided critical insights into host processes, including protein trafficking and turnover. Mouse mammary tumor virus (MMTV) is a betaretrovirus that encodes a functional 98-amino-acid signal peptide (SP). MMTV SP is generated from both Rem and envelope precursor pr...

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Detalles Bibliográficos
Autores principales: Das, Poulami, Xu, Wendy Kaichun, Gautam, Amit Kumar Singh, Lozano, Mary M., Dudley, Jaquelin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725593/
https://www.ncbi.nlm.nih.gov/pubmed/35089078
http://dx.doi.org/10.1128/mBio.02953-21

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