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A Retrotranslocation Assay That Predicts Defective VCP/p97-Mediated Trafficking of a Retroviral Signal Peptide
Studies of viral replication have provided critical insights into host processes, including protein trafficking and turnover. Mouse mammary tumor virus (MMTV) is a betaretrovirus that encodes a functional 98-amino-acid signal peptide (SP). MMTV SP is generated from both Rem and envelope precursor pr...
Autores principales: | Das, Poulami, Xu, Wendy Kaichun, Gautam, Amit Kumar Singh, Lozano, Mary M., Dudley, Jaquelin P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725593/ https://www.ncbi.nlm.nih.gov/pubmed/35089078 http://dx.doi.org/10.1128/mBio.02953-21 |
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