Enhanced visibility through microbubble-induced photoacoustic fluctuation imaging

A photoacoustic contrast mechanism is presented based on the photoacoustic fluctuations induced by microbubbles flowing inside a micro-vessel filled with a continuous absorber. It is demonstrated that the standard deviation of a homogeneous absorber mixed with microbubbles increases non-linearly as...

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Detalles Bibliográficos
Autores principales: Inzunza-Ibarra, Marco A., Navarro-Becerra, J. Angel, Narumanchi, Venkatalakshmi, Bottenus, Nick, Murray, Todd W., Borden, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Acoustical Society of America 2022
Materias:
Biomedical Acoustics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725790/
https://www.ncbi.nlm.nih.gov/pubmed/35005712
http://dx.doi.org/10.1121/10.0009129
Descripción
Sumario:A photoacoustic contrast mechanism is presented based on the photoacoustic fluctuations induced by microbubbles flowing inside a micro-vessel filled with a continuous absorber. It is demonstrated that the standard deviation of a homogeneous absorber mixed with microbubbles increases non-linearly as the microbubble concentration and microbubble size is increased. This effect is then utilized to perform photoacoustic fluctuation imaging with increased visibility and contrast of a blood flow phantom.

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