Enhanced visibility through microbubble-induced photoacoustic fluctuation imaging

A photoacoustic contrast mechanism is presented based on the photoacoustic fluctuations induced by microbubbles flowing inside a micro-vessel filled with a continuous absorber. It is demonstrated that the standard deviation of a homogeneous absorber mixed with microbubbles increases non-linearly as...

Descripción completa

Detalles Bibliográficos
Autores principales: Inzunza-Ibarra, Marco A., Navarro-Becerra, J. Angel, Narumanchi, Venkatalakshmi, Bottenus, Nick, Murray, Todd W., Borden, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Acoustical Society of America 2022
Materias:
Biomedical Acoustics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725790/
https://www.ncbi.nlm.nih.gov/pubmed/35005712
http://dx.doi.org/10.1121/10.0009129
_version_ 1784626183891058688
author Inzunza-Ibarra, Marco A.
Navarro-Becerra, J. Angel
Narumanchi, Venkatalakshmi
Bottenus, Nick
Murray, Todd W.
Borden, Mark A.
author_facet Inzunza-Ibarra, Marco A.
Navarro-Becerra, J. Angel
Narumanchi, Venkatalakshmi
Bottenus, Nick
Murray, Todd W.
Borden, Mark A.
author_sort Inzunza-Ibarra, Marco A.
collection PubMed
description A photoacoustic contrast mechanism is presented based on the photoacoustic fluctuations induced by microbubbles flowing inside a micro-vessel filled with a continuous absorber. It is demonstrated that the standard deviation of a homogeneous absorber mixed with microbubbles increases non-linearly as the microbubble concentration and microbubble size is increased. This effect is then utilized to perform photoacoustic fluctuation imaging with increased visibility and contrast of a blood flow phantom.
format Online
Article
Text
id pubmed-8725790
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Acoustical Society of America
record_format MEDLINE/PubMed
spelling pubmed-87257902022-01-05 Enhanced visibility through microbubble-induced photoacoustic fluctuation imaging Inzunza-Ibarra, Marco A. Navarro-Becerra, J. Angel Narumanchi, Venkatalakshmi Bottenus, Nick Murray, Todd W. Borden, Mark A. JASA Express Lett Biomedical Acoustics A photoacoustic contrast mechanism is presented based on the photoacoustic fluctuations induced by microbubbles flowing inside a micro-vessel filled with a continuous absorber. It is demonstrated that the standard deviation of a homogeneous absorber mixed with microbubbles increases non-linearly as the microbubble concentration and microbubble size is increased. This effect is then utilized to perform photoacoustic fluctuation imaging with increased visibility and contrast of a blood flow phantom. Acoustical Society of America 2022-01 2022-01-03 /pmc/articles/PMC8725790/ /pubmed/35005712 http://dx.doi.org/10.1121/10.0009129 Text en © 2022 Author(s). 2691-1191/2022/2(1)/012001/6 https://creativecommons.org/licenses/by/4.0/All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Biomedical Acoustics
Inzunza-Ibarra, Marco A.
Navarro-Becerra, J. Angel
Narumanchi, Venkatalakshmi
Bottenus, Nick
Murray, Todd W.
Borden, Mark A.
Enhanced visibility through microbubble-induced photoacoustic fluctuation imaging
title Enhanced visibility through microbubble-induced photoacoustic fluctuation imaging
title_full Enhanced visibility through microbubble-induced photoacoustic fluctuation imaging
title_fullStr Enhanced visibility through microbubble-induced photoacoustic fluctuation imaging
title_full_unstemmed Enhanced visibility through microbubble-induced photoacoustic fluctuation imaging
title_short Enhanced visibility through microbubble-induced photoacoustic fluctuation imaging
title_sort enhanced visibility through microbubble-induced photoacoustic fluctuation imaging
topic Biomedical Acoustics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725790/
https://www.ncbi.nlm.nih.gov/pubmed/35005712
http://dx.doi.org/10.1121/10.0009129
work_keys_str_mv AT inzunzaibarramarcoa enhancedvisibilitythroughmicrobubbleinducedphotoacousticfluctuationimaging
AT navarrobecerrajangel enhancedvisibilitythroughmicrobubbleinducedphotoacousticfluctuationimaging
AT narumanchivenkatalakshmi enhancedvisibilitythroughmicrobubbleinducedphotoacousticfluctuationimaging
AT bottenusnick enhancedvisibilitythroughmicrobubbleinducedphotoacousticfluctuationimaging
AT murraytoddw enhancedvisibilitythroughmicrobubbleinducedphotoacousticfluctuationimaging
AT bordenmarka enhancedvisibilitythroughmicrobubbleinducedphotoacousticfluctuationimaging

Ejemplares similares