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Cucurbitacin B regulates lung cancer cell proliferation and apoptosis via inhibiting the IL-6/STAT3 pathway through the lncRNA XIST/miR-let-7c axis
CONTEXT: Lung cancer, the most common type of cancer, has a high mortality rate. Cucurbitacin B (CuB), a natural compound extracted from Cucurbitaceae plants, has antitumor effects. OBJECTIVE: We investigated the role of CuB on lung cancer and its potential mechanisms. MATERIALS AND METHODS: A549 ce...
Autores principales: | Liu, Jian-Hua, Li, Chen, Cao, Liang, Zhang, Chang-Hong, Zhang, Zhi-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725843/ https://www.ncbi.nlm.nih.gov/pubmed/34967707 http://dx.doi.org/10.1080/13880209.2021.2016866 |
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