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Cucurbitacin B regulates lung cancer cell proliferation and apoptosis via inhibiting the IL-6/STAT3 pathway through the lncRNA XIST/miR-let-7c axis

CONTEXT: Lung cancer, the most common type of cancer, has a high mortality rate. Cucurbitacin B (CuB), a natural compound extracted from Cucurbitaceae plants, has antitumor effects. OBJECTIVE: We investigated the role of CuB on lung cancer and its potential mechanisms. MATERIALS AND METHODS: A549 ce...

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Detalles Bibliográficos
Autores principales: Liu, Jian-Hua, Li, Chen, Cao, Liang, Zhang, Chang-Hong, Zhang, Zhi-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725843/
https://www.ncbi.nlm.nih.gov/pubmed/34967707
http://dx.doi.org/10.1080/13880209.2021.2016866

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