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Celastrol-conjugated chitosan oligosaccharide for the treatment of pancreatic cancer

Celastrol is a promising antitumor drug candidate, but the poor water solubility and cytotoxicity limit its clinical application. Herein, we synthesized a Celastrol (Cel)-chitosan oligosaccharide (CSO) conjugate (Cel-CSO) for drug delivery. Celastrol was conjugated to a CSO backbone via amide bond f...

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Detalles Bibliográficos
Autores principales:	Zeng, Xiaohu, Zhu, Xin, Tian, Qikang, Tan, Xiaoke, Sun, Ning, Yan, Min, Zhao, Junwei, Wu, Xiangxiang, Li, Ruiqin, Zhang, Zhenqiang, Zeng, Huahui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725862/ https://www.ncbi.nlm.nih.gov/pubmed/34964425 http://dx.doi.org/10.1080/10717544.2021.2018521

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