Enterovirus A71 2B Inhibits Interferon-Activated JAK/STAT Signaling by Inducing Caspase-3-Dependent Karyopherin-α1 Degradation

Enterovirus A71 (EV-A71) is a major pathogen that causes the hand, foot, and mouth disease, which could be fatal with neurological complications in children. The underlying mechanism for the severe pathogenicity remains obscure, but impaired or aberrant innate immunity is considered to play a key ro...

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Detalles Bibliográficos
Autores principales: Sun, Menghuai, Lin, Qian, Wang, Chunyang, Xing, Jiao, Yan, Kunlong, Liu, Zhifeng, Jin, Yu, Cardona, Carol J., Xing, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725996/
https://www.ncbi.nlm.nih.gov/pubmed/34992585
http://dx.doi.org/10.3389/fmicb.2021.762869

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