Heterologous prime-boost vaccination against COVID-19: is it safe and reliable?

Throughout the globe, many nations are struggling to cope with the consecutive waves of the COVID-19. Several vaccines have been employed to overcome this ongoing pandemic and are available as single and double-dose inoculations; however, homologous vaccine efficacy is being reconsidered due to the...

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Detalles Bibliográficos
Autores principales: Choudhary, Om Prakash, Priyanka, Ahmed, Jivan Q., Mohammed, Teroj A., Singh, Indraj, Rodriguez-Morales, Alfonso J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726007/
https://www.ncbi.nlm.nih.gov/pubmed/34898381
http://dx.doi.org/10.1080/21645515.2021.2007015
Descripción
Sumario:Throughout the globe, many nations are struggling to cope with the consecutive waves of the COVID-19. Several vaccines have been employed to overcome this ongoing pandemic and are available as single and double-dose inoculations; however, homologous vaccine efficacy is being reconsidered due to the rapidly emerging SARS-CoV-2 variants. Many studies have been conducted on the heterologous prime-boost vaccine regimens and have shown good efficacy results against COVID-19. This article aims to highlight the safety and reliability of heterologous prime-boost vaccination against COVID-19. We have also made some recommendations towards using these combinations of vaccines for the global mitigation of the subsequent waves of COVID-19.

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