Cargando…
Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer
BACKGROUND: The present paper reports on analysis of 184 patients who were diagnosed with endometrial cancer. The main objective of this study was to address parameter V(rec(30Gy)) which determines a volume of the rectum irradiated with a dose of 30 Gy during radiotherapy. MATERIALS AND METHODS: All...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Via Medica
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726440/ https://www.ncbi.nlm.nih.gov/pubmed/34992861 http://dx.doi.org/10.5603/RPOR.a2021.0106 |
_version_ | 1784626323601227776 |
---|---|
author | Łukowiak, Magdalena Galant, Grzegorz Jezierska, Karolina Falco, Michał Woźniak, Piotr Podraza, Wojciech Kowalski-Stankiewicz, Janusz P. |
author_facet | Łukowiak, Magdalena Galant, Grzegorz Jezierska, Karolina Falco, Michał Woźniak, Piotr Podraza, Wojciech Kowalski-Stankiewicz, Janusz P. |
author_sort | Łukowiak, Magdalena |
collection | PubMed |
description | BACKGROUND: The present paper reports on analysis of 184 patients who were diagnosed with endometrial cancer. The main objective of this study was to address parameter V(rec(30Gy)) which determines a volume of the rectum irradiated with a dose of 30 Gy during radiotherapy. MATERIALS AND METHODS: All patients were irradiated with an IMRT technique on linear accelerators. The planning target volume (PTV) contour was determined by a radiation oncologist. The clinical target volume (CTV) was drawn on CT images obtained in a prone position. For statistical analysis, appropriate tests (e.g. the Shapiro-Wilk, Wilcoxon) were used. RESULTS AND DISCUSSION: The performed analysis showed that the recommended condition for V(rec(30Gy)) is met only in 3% of patients and the observed median value exceeds 90%. The obtained results were compared with the studies in which the V(rec(30Gy)) values were related to various radiotherapy techniques. CONCLUSIONS: The analysis showed that the condition for V(rec(30Gy)) is satisfied in the case of only 3% of patients. Due to the difficulty with meeting the condition, it should be reconsidered based on real results. |
format | Online Article Text |
id | pubmed-8726440 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Via Medica |
record_format | MEDLINE/PubMed |
spelling | pubmed-87264402022-01-05 Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer Łukowiak, Magdalena Galant, Grzegorz Jezierska, Karolina Falco, Michał Woźniak, Piotr Podraza, Wojciech Kowalski-Stankiewicz, Janusz P. Rep Pract Oncol Radiother Research Paper BACKGROUND: The present paper reports on analysis of 184 patients who were diagnosed with endometrial cancer. The main objective of this study was to address parameter V(rec(30Gy)) which determines a volume of the rectum irradiated with a dose of 30 Gy during radiotherapy. MATERIALS AND METHODS: All patients were irradiated with an IMRT technique on linear accelerators. The planning target volume (PTV) contour was determined by a radiation oncologist. The clinical target volume (CTV) was drawn on CT images obtained in a prone position. For statistical analysis, appropriate tests (e.g. the Shapiro-Wilk, Wilcoxon) were used. RESULTS AND DISCUSSION: The performed analysis showed that the recommended condition for V(rec(30Gy)) is met only in 3% of patients and the observed median value exceeds 90%. The obtained results were compared with the studies in which the V(rec(30Gy)) values were related to various radiotherapy techniques. CONCLUSIONS: The analysis showed that the condition for V(rec(30Gy)) is satisfied in the case of only 3% of patients. Due to the difficulty with meeting the condition, it should be reconsidered based on real results. Via Medica 2021-12-30 /pmc/articles/PMC8726440/ /pubmed/34992861 http://dx.doi.org/10.5603/RPOR.a2021.0106 Text en © 2021 Greater Poland Cancer Centre https://creativecommons.org/licenses/by-nc-nd/4.0/This article is available in open access under Creative Common Attribution-Non-Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0) license, allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially |
spellingShingle | Research Paper Łukowiak, Magdalena Galant, Grzegorz Jezierska, Karolina Falco, Michał Woźniak, Piotr Podraza, Wojciech Kowalski-Stankiewicz, Janusz P. Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer |
title | Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer |
title_full | Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer |
title_fullStr | Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer |
title_full_unstemmed | Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer |
title_short | Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer |
title_sort | evaluation of the rectal v30 parameter in patients diagnosed with postoperative endometrial cancer |
topic | Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726440/ https://www.ncbi.nlm.nih.gov/pubmed/34992861 http://dx.doi.org/10.5603/RPOR.a2021.0106 |
work_keys_str_mv | AT łukowiakmagdalena evaluationoftherectalv30parameterinpatientsdiagnosedwithpostoperativeendometrialcancer AT galantgrzegorz evaluationoftherectalv30parameterinpatientsdiagnosedwithpostoperativeendometrialcancer AT jezierskakarolina evaluationoftherectalv30parameterinpatientsdiagnosedwithpostoperativeendometrialcancer AT falcomichał evaluationoftherectalv30parameterinpatientsdiagnosedwithpostoperativeendometrialcancer AT wozniakpiotr evaluationoftherectalv30parameterinpatientsdiagnosedwithpostoperativeendometrialcancer AT podrazawojciech evaluationoftherectalv30parameterinpatientsdiagnosedwithpostoperativeendometrialcancer AT kowalskistankiewiczjanuszp evaluationoftherectalv30parameterinpatientsdiagnosedwithpostoperativeendometrialcancer |