Cargando…

Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer

BACKGROUND: The present paper reports on analysis of 184 patients who were diagnosed with endometrial cancer. The main objective of this study was to address parameter V(rec(30Gy)) which determines a volume of the rectum irradiated with a dose of 30 Gy during radiotherapy. MATERIALS AND METHODS: All...

Descripción completa

Detalles Bibliográficos
Autores principales: Łukowiak, Magdalena, Galant, Grzegorz, Jezierska, Karolina, Falco, Michał, Woźniak, Piotr, Podraza, Wojciech, Kowalski-Stankiewicz, Janusz P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Via Medica 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726440/
https://www.ncbi.nlm.nih.gov/pubmed/34992861
http://dx.doi.org/10.5603/RPOR.a2021.0106
_version_ 1784626323601227776
author Łukowiak, Magdalena
Galant, Grzegorz
Jezierska, Karolina
Falco, Michał
Woźniak, Piotr
Podraza, Wojciech
Kowalski-Stankiewicz, Janusz P.
author_facet Łukowiak, Magdalena
Galant, Grzegorz
Jezierska, Karolina
Falco, Michał
Woźniak, Piotr
Podraza, Wojciech
Kowalski-Stankiewicz, Janusz P.
author_sort Łukowiak, Magdalena
collection PubMed
description BACKGROUND: The present paper reports on analysis of 184 patients who were diagnosed with endometrial cancer. The main objective of this study was to address parameter V(rec(30Gy)) which determines a volume of the rectum irradiated with a dose of 30 Gy during radiotherapy. MATERIALS AND METHODS: All patients were irradiated with an IMRT technique on linear accelerators. The planning target volume (PTV) contour was determined by a radiation oncologist. The clinical target volume (CTV) was drawn on CT images obtained in a prone position. For statistical analysis, appropriate tests (e.g. the Shapiro-Wilk, Wilcoxon) were used. RESULTS AND DISCUSSION: The performed analysis showed that the recommended condition for V(rec(30Gy)) is met only in 3% of patients and the observed median value exceeds 90%. The obtained results were compared with the studies in which the V(rec(30Gy)) values were related to various radiotherapy techniques. CONCLUSIONS: The analysis showed that the condition for V(rec(30Gy)) is satisfied in the case of only 3% of patients. Due to the difficulty with meeting the condition, it should be reconsidered based on real results.
format Online
Article
Text
id pubmed-8726440
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Via Medica
record_format MEDLINE/PubMed
spelling pubmed-87264402022-01-05 Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer Łukowiak, Magdalena Galant, Grzegorz Jezierska, Karolina Falco, Michał Woźniak, Piotr Podraza, Wojciech Kowalski-Stankiewicz, Janusz P. Rep Pract Oncol Radiother Research Paper BACKGROUND: The present paper reports on analysis of 184 patients who were diagnosed with endometrial cancer. The main objective of this study was to address parameter V(rec(30Gy)) which determines a volume of the rectum irradiated with a dose of 30 Gy during radiotherapy. MATERIALS AND METHODS: All patients were irradiated with an IMRT technique on linear accelerators. The planning target volume (PTV) contour was determined by a radiation oncologist. The clinical target volume (CTV) was drawn on CT images obtained in a prone position. For statistical analysis, appropriate tests (e.g. the Shapiro-Wilk, Wilcoxon) were used. RESULTS AND DISCUSSION: The performed analysis showed that the recommended condition for V(rec(30Gy)) is met only in 3% of patients and the observed median value exceeds 90%. The obtained results were compared with the studies in which the V(rec(30Gy)) values were related to various radiotherapy techniques. CONCLUSIONS: The analysis showed that the condition for V(rec(30Gy)) is satisfied in the case of only 3% of patients. Due to the difficulty with meeting the condition, it should be reconsidered based on real results. Via Medica 2021-12-30 /pmc/articles/PMC8726440/ /pubmed/34992861 http://dx.doi.org/10.5603/RPOR.a2021.0106 Text en © 2021 Greater Poland Cancer Centre https://creativecommons.org/licenses/by-nc-nd/4.0/This article is available in open access under Creative Common Attribution-Non-Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0) license, allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially
spellingShingle Research Paper
Łukowiak, Magdalena
Galant, Grzegorz
Jezierska, Karolina
Falco, Michał
Woźniak, Piotr
Podraza, Wojciech
Kowalski-Stankiewicz, Janusz P.
Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer
title Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer
title_full Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer
title_fullStr Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer
title_full_unstemmed Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer
title_short Evaluation of the rectal V30 parameter in patients diagnosed with postoperative endometrial cancer
title_sort evaluation of the rectal v30 parameter in patients diagnosed with postoperative endometrial cancer
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726440/
https://www.ncbi.nlm.nih.gov/pubmed/34992861
http://dx.doi.org/10.5603/RPOR.a2021.0106
work_keys_str_mv AT łukowiakmagdalena evaluationoftherectalv30parameterinpatientsdiagnosedwithpostoperativeendometrialcancer
AT galantgrzegorz evaluationoftherectalv30parameterinpatientsdiagnosedwithpostoperativeendometrialcancer
AT jezierskakarolina evaluationoftherectalv30parameterinpatientsdiagnosedwithpostoperativeendometrialcancer
AT falcomichał evaluationoftherectalv30parameterinpatientsdiagnosedwithpostoperativeendometrialcancer
AT wozniakpiotr evaluationoftherectalv30parameterinpatientsdiagnosedwithpostoperativeendometrialcancer
AT podrazawojciech evaluationoftherectalv30parameterinpatientsdiagnosedwithpostoperativeendometrialcancer
AT kowalskistankiewiczjanuszp evaluationoftherectalv30parameterinpatientsdiagnosedwithpostoperativeendometrialcancer