CNNM proteins selectively bind to the TRPM7 channel to stimulate divalent cation entry into cells

Magnesium is essential for cellular life, but how it is homeostatically controlled still remains poorly understood. Here, we report that members of CNNM family, which have been controversially implicated in both cellular Mg(2+) influx and efflux, selectively bind to the TRPM7 channel to stimulate di...

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Detalles Bibliográficos
Autores principales: Bai, Zhiyong, Feng, Jianlin, Franken, Gijs A. C., Al’Saadi, Namariq, Cai, Na, Yu, Albert S., Lou, Liping, Komiya, Yuko, Hoenderop, Joost G. J., de Baaij, Jeroen H. F., Yue, Lixia, Runnels, Loren W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726484/
https://www.ncbi.nlm.nih.gov/pubmed/34928937
http://dx.doi.org/10.1371/journal.pbio.3001496

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