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Dynamical analysis of coronavirus disease with crowding effect, and vaccination: a study of third strain

Countries affected by the coronavirus epidemic have reported many infected cases and deaths based on world health statistics. The crowding factor, which we named "crowding effects," plays a significant role in spreading the diseases. However, the introduction of vaccines marks a turning po...

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Autores principales: Raza, Ali, Rafiq, Muhammad, Awrejcewicz, Jan, Ahmed, Nauman, Mohsin, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726531/
https://www.ncbi.nlm.nih.gov/pubmed/35002076
http://dx.doi.org/10.1007/s11071-021-07108-5
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author Raza, Ali
Rafiq, Muhammad
Awrejcewicz, Jan
Ahmed, Nauman
Mohsin, Muhammad
author_facet Raza, Ali
Rafiq, Muhammad
Awrejcewicz, Jan
Ahmed, Nauman
Mohsin, Muhammad
author_sort Raza, Ali
collection PubMed
description Countries affected by the coronavirus epidemic have reported many infected cases and deaths based on world health statistics. The crowding factor, which we named "crowding effects," plays a significant role in spreading the diseases. However, the introduction of vaccines marks a turning point in the rate of spread of coronavirus infections. Modeling both effects is vastly essential as it directly impacts the overall population of the studied region. To determine the peak of the infection curve by considering the third strain, we develop a mathematical model (susceptible–infected–vaccinated–recovered) with reported cases from August 01, 2021, till August 29, 2021. The nonlinear incidence rate with the inclusion of both effects is the best approach to analyze the dynamics. The model's positivity, boundedness, existence, uniqueness, and stability (local and global) are addressed with the help of a reproduction number. In addition, the strength number and second derivative Lyapunov analysis are examined, and the model was found to be asymptotically stable. The suggested parameters efficiently control the active cases of the third strain in Pakistan. It was shown that a systematic vaccination program regulates the infection rate. However, the crowding effect reduces the impact of vaccination. The present results show that the model can be applied to other countries' data to predict the infection rate.
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spelling pubmed-87265312022-01-05 Dynamical analysis of coronavirus disease with crowding effect, and vaccination: a study of third strain Raza, Ali Rafiq, Muhammad Awrejcewicz, Jan Ahmed, Nauman Mohsin, Muhammad Nonlinear Dyn Original Paper Countries affected by the coronavirus epidemic have reported many infected cases and deaths based on world health statistics. The crowding factor, which we named "crowding effects," plays a significant role in spreading the diseases. However, the introduction of vaccines marks a turning point in the rate of spread of coronavirus infections. Modeling both effects is vastly essential as it directly impacts the overall population of the studied region. To determine the peak of the infection curve by considering the third strain, we develop a mathematical model (susceptible–infected–vaccinated–recovered) with reported cases from August 01, 2021, till August 29, 2021. The nonlinear incidence rate with the inclusion of both effects is the best approach to analyze the dynamics. The model's positivity, boundedness, existence, uniqueness, and stability (local and global) are addressed with the help of a reproduction number. In addition, the strength number and second derivative Lyapunov analysis are examined, and the model was found to be asymptotically stable. The suggested parameters efficiently control the active cases of the third strain in Pakistan. It was shown that a systematic vaccination program regulates the infection rate. However, the crowding effect reduces the impact of vaccination. The present results show that the model can be applied to other countries' data to predict the infection rate. Springer Netherlands 2022-01-04 2022 /pmc/articles/PMC8726531/ /pubmed/35002076 http://dx.doi.org/10.1007/s11071-021-07108-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Paper
Raza, Ali
Rafiq, Muhammad
Awrejcewicz, Jan
Ahmed, Nauman
Mohsin, Muhammad
Dynamical analysis of coronavirus disease with crowding effect, and vaccination: a study of third strain
title Dynamical analysis of coronavirus disease with crowding effect, and vaccination: a study of third strain
title_full Dynamical analysis of coronavirus disease with crowding effect, and vaccination: a study of third strain
title_fullStr Dynamical analysis of coronavirus disease with crowding effect, and vaccination: a study of third strain
title_full_unstemmed Dynamical analysis of coronavirus disease with crowding effect, and vaccination: a study of third strain
title_short Dynamical analysis of coronavirus disease with crowding effect, and vaccination: a study of third strain
title_sort dynamical analysis of coronavirus disease with crowding effect, and vaccination: a study of third strain
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726531/
https://www.ncbi.nlm.nih.gov/pubmed/35002076
http://dx.doi.org/10.1007/s11071-021-07108-5
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