Direct homophilic interaction of LAMP2A with the two-domain architecture revealed by site-directed photo-crosslinks and steric hindrances in mammalian cells

LAMP1 (lysosomal-associated membrane protein 1) and LAMP2 are the most abundant protein components of lysosome membranes. Both LAMPs have common structures consisting of a large lumenal domain composed of two domains (N-domain and C-domain, which are membrane-distal and -proximal, respectively), bot...

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Detalles Bibliográficos
Autores principales: Terasawa, Kazue, Kato, Yuji, Ikami, Yuta, Sakamoto, Kensaku, Ohtake, Kazumasa, Kusano, Seisuke, Tomabechi, Yuri, Kukimoto-Niino, Mutsuko, Shirouzu, Mikako, Guan, Jun-Lin, Kobayashi, Toshihide, Iwata, Takanori, Watabe, Tetsuro, Yokoyama, Shigeyuki, Hara-Yokoyama, Miki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726616/
https://www.ncbi.nlm.nih.gov/pubmed/33849387
http://dx.doi.org/10.1080/15548627.2021.1911017

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