Cargando…
The ingenious ULKs: expanding the repertoire of the ULK complex with phosphoproteomics
The mammalian ULK kinase complex is the most upstream component in the macroautophagy/autophagy signaling pathway. ULK1 and homolog ULK2, the sole serine/threonine kinases in autophagy, transduce an array of autophagy-inducing stimuli to downstream autophagic machinery, regulating autophagy from aut...
Autores principales: | Mercer, Thomas J., Tooze, Sharon A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726633/ https://www.ncbi.nlm.nih.gov/pubmed/34520329 http://dx.doi.org/10.1080/15548627.2021.1968615 |
Ejemplares similares
-
Regulating RIPK1: another way in which ULK1 contributes to survival
por: Wu, Wenxian, et al.
Publicado: (2020) -
GABARAP activates ULK1 and traffics from the centrosome dependent on Golgi partners WAC and GOLGA2/GM130
por: Joachim, Justin, et al.
Publicado: (2016) -
A mitochondrial-associated link between an effector caspase and autophagic flux
por: DeVorkin, Lindsay, et al.
Publicado: (2014) -
TORC2-SGK-1 signaling integrates external signals to regulate autophagic turnover of mitochondria via mtROS
por: Heimbucher, Thomas, et al.
Publicado: (2020) -
Lipid droplets promote efficient mitophagy
por: Long, Maeve, et al.
Publicado: (2022)