TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy

Macroautophagy/autophagy and necroptosis represent two opposing cellular s tress responses. Whereas autophagy primarily fulfills a cyto-protective function, necroptosis is a form of regulated cell death induced via death receptors. Here, we aimed at investigating the molecular crosstalk between thes...

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Detalles Bibliográficos
Autores principales: Wu, Wenxian, Wang, Xiaojing, Sun, Yadong, Berleth, Niklas, Deitersen, Jana, Schlütermann, David, Stuhldreier, Fabian, Wallot-Hieke, Nora, José Mendiburo, María, Cox, Jan, Peter, Christoph, Bergmann, Ann Kathrin, Stork, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726653/
https://www.ncbi.nlm.nih.gov/pubmed/33779513
http://dx.doi.org/10.1080/15548627.2021.1899667

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