V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis

Glioblastoma (GBM), a very aggressive and incurable tumor, often results from constitutive activation of EGFR (epidermal growth factor receptor) and of phosphoinositide 3-kinase (PI3K). To understand the role of autophagy in the pathogenesis of glial tumors in vivo, we used an established Drosophila...

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Detalles Bibliográficos
Autores principales: Formica, Miriam, Storaci, Alessandra Maria, Bertolini, Irene, Carminati, Francesca, Knævelsrud, Helene, Vaira, Valentina, Vaccari, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726678/
https://www.ncbi.nlm.nih.gov/pubmed/33978540
http://dx.doi.org/10.1080/15548627.2021.1918915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726678/
https://www.ncbi.nlm.nih.gov/pubmed/33978540
http://dx.doi.org/10.1080/15548627.2021.1918915

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