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Lasia spinosa Chemical Composition and Therapeutic Potential: A Literature-Based Review

Lasia spinosa (L.) is used ethnobotanically for the treatment of various diseases, including rheumatoid arthritis, inflammation of the lungs, bleeding cough, hemorrhoids, intestinal diseases, stomach pain, and uterine cancer. This review is aimed at summarizing phytochemistry and pharmacological dat...

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Autores principales: Hossain, Rajib, Quispe, Cristina, Herrera-Bravo, Jesús, Islam, Md. Shahazul, Sarkar, Chandan, Islam, Muhammad Torequl, Martorell, Miquel, Cruz-Martins, Natália, Al-Harrasi, Ahmed, Al-Rawahi, Ahmed, Sharifi-Rad, Javad, Ibrayeva, Manshuk, Daştan, Sevgi Durna, Alshehri, Mohammed M., Calina, Daniela, Cho, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727140/
https://www.ncbi.nlm.nih.gov/pubmed/34992714
http://dx.doi.org/10.1155/2021/1602437
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author Hossain, Rajib
Quispe, Cristina
Herrera-Bravo, Jesús
Islam, Md. Shahazul
Sarkar, Chandan
Islam, Muhammad Torequl
Martorell, Miquel
Cruz-Martins, Natália
Al-Harrasi, Ahmed
Al-Rawahi, Ahmed
Sharifi-Rad, Javad
Ibrayeva, Manshuk
Daştan, Sevgi Durna
Alshehri, Mohammed M.
Calina, Daniela
Cho, William C.
author_facet Hossain, Rajib
Quispe, Cristina
Herrera-Bravo, Jesús
Islam, Md. Shahazul
Sarkar, Chandan
Islam, Muhammad Torequl
Martorell, Miquel
Cruz-Martins, Natália
Al-Harrasi, Ahmed
Al-Rawahi, Ahmed
Sharifi-Rad, Javad
Ibrayeva, Manshuk
Daştan, Sevgi Durna
Alshehri, Mohammed M.
Calina, Daniela
Cho, William C.
author_sort Hossain, Rajib
collection PubMed
description Lasia spinosa (L.) is used ethnobotanically for the treatment of various diseases, including rheumatoid arthritis, inflammation of the lungs, bleeding cough, hemorrhoids, intestinal diseases, stomach pain, and uterine cancer. This review is aimed at summarizing phytochemistry and pharmacological data with their molecular mechanisms of action. A search was performed in databases such as PubMed, Science Direct, and Google Scholar using the keywords: “Lasia spinosa,” then combined with “ethnopharmacological use,” “phytochemistry,” and “pharmacological activity.” This updated review included studies with in vitro, ex vivo, and in vivo experiments with compounds of known concentration and highlighted pharmacological mechanisms. The research results showed that L. spinosa contains many important nutritional and phytochemical components such as alkanes, aldehydes, alkaloids, carotenoids, flavonoids, fatty acids, ketones, lignans, phenolics, terpenoids, steroids, and volatile oil with excellent bioactivity. The importance of this review lies in the fact that scientific pharmacological evidence supports the fact that the plant has antioxidant, anti-inflammatory, antimicrobial, cytotoxic, antidiarrheal, antihelminthic, antidiabetic, antihyperlipidemic, and antinociceptive effects, while protecting the gastrointestinal system and reproductive. Regarding future toxicological and safety data, more research is needed, including studies on human subjects. In light of these data, L. spinosa can be considered a medicinal plant with effective bioactives for the adjuvant treatment of various diseases in humans.
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spelling pubmed-87271402022-01-05 Lasia spinosa Chemical Composition and Therapeutic Potential: A Literature-Based Review Hossain, Rajib Quispe, Cristina Herrera-Bravo, Jesús Islam, Md. Shahazul Sarkar, Chandan Islam, Muhammad Torequl Martorell, Miquel Cruz-Martins, Natália Al-Harrasi, Ahmed Al-Rawahi, Ahmed Sharifi-Rad, Javad Ibrayeva, Manshuk Daştan, Sevgi Durna Alshehri, Mohammed M. Calina, Daniela Cho, William C. Oxid Med Cell Longev Review Article Lasia spinosa (L.) is used ethnobotanically for the treatment of various diseases, including rheumatoid arthritis, inflammation of the lungs, bleeding cough, hemorrhoids, intestinal diseases, stomach pain, and uterine cancer. This review is aimed at summarizing phytochemistry and pharmacological data with their molecular mechanisms of action. A search was performed in databases such as PubMed, Science Direct, and Google Scholar using the keywords: “Lasia spinosa,” then combined with “ethnopharmacological use,” “phytochemistry,” and “pharmacological activity.” This updated review included studies with in vitro, ex vivo, and in vivo experiments with compounds of known concentration and highlighted pharmacological mechanisms. The research results showed that L. spinosa contains many important nutritional and phytochemical components such as alkanes, aldehydes, alkaloids, carotenoids, flavonoids, fatty acids, ketones, lignans, phenolics, terpenoids, steroids, and volatile oil with excellent bioactivity. The importance of this review lies in the fact that scientific pharmacological evidence supports the fact that the plant has antioxidant, anti-inflammatory, antimicrobial, cytotoxic, antidiarrheal, antihelminthic, antidiabetic, antihyperlipidemic, and antinociceptive effects, while protecting the gastrointestinal system and reproductive. Regarding future toxicological and safety data, more research is needed, including studies on human subjects. In light of these data, L. spinosa can be considered a medicinal plant with effective bioactives for the adjuvant treatment of various diseases in humans. Hindawi 2021-12-28 /pmc/articles/PMC8727140/ /pubmed/34992714 http://dx.doi.org/10.1155/2021/1602437 Text en Copyright © 2021 Rajib Hossain et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Hossain, Rajib
Quispe, Cristina
Herrera-Bravo, Jesús
Islam, Md. Shahazul
Sarkar, Chandan
Islam, Muhammad Torequl
Martorell, Miquel
Cruz-Martins, Natália
Al-Harrasi, Ahmed
Al-Rawahi, Ahmed
Sharifi-Rad, Javad
Ibrayeva, Manshuk
Daştan, Sevgi Durna
Alshehri, Mohammed M.
Calina, Daniela
Cho, William C.
Lasia spinosa Chemical Composition and Therapeutic Potential: A Literature-Based Review
title Lasia spinosa Chemical Composition and Therapeutic Potential: A Literature-Based Review
title_full Lasia spinosa Chemical Composition and Therapeutic Potential: A Literature-Based Review
title_fullStr Lasia spinosa Chemical Composition and Therapeutic Potential: A Literature-Based Review
title_full_unstemmed Lasia spinosa Chemical Composition and Therapeutic Potential: A Literature-Based Review
title_short Lasia spinosa Chemical Composition and Therapeutic Potential: A Literature-Based Review
title_sort lasia spinosa chemical composition and therapeutic potential: a literature-based review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727140/
https://www.ncbi.nlm.nih.gov/pubmed/34992714
http://dx.doi.org/10.1155/2021/1602437
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