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Human genetic variant E756del in the ion channel PIEZO1 not associated with protection from severe malaria in a large Ghanaian study
Recently, a common genetic variant E756del in the human gene PIEZO1 was associated with protection from severe malaria. Here, we performed a genetic association study of this gain-of-function variant in a large case-control study including 4149 children from the Ashanti Region in Ghana, West Africa....
Autores principales: | Thye, Thorsten, Evans, Jennifer A., Ruge, Gerd, Loag, Wibke, Ansong, Daniel, Agbenyega, Tsiri, Horstmann, Rolf D., May, Jürgen, Schuldt, Kathrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727285/ https://www.ncbi.nlm.nih.gov/pubmed/34230590 http://dx.doi.org/10.1038/s10038-021-00958-2 |
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