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Human genetic variant E756del in the ion channel PIEZO1 not associated with protection from severe malaria in a large Ghanaian study

Recently, a common genetic variant E756del in the human gene PIEZO1 was associated with protection from severe malaria. Here, we performed a genetic association study of this gain-of-function variant in a large case-control study including 4149 children from the Ashanti Region in Ghana, West Africa....

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Detalles Bibliográficos
Autores principales: Thye, Thorsten, Evans, Jennifer A., Ruge, Gerd, Loag, Wibke, Ansong, Daniel, Agbenyega, Tsiri, Horstmann, Rolf D., May, Jürgen, Schuldt, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727285/
https://www.ncbi.nlm.nih.gov/pubmed/34230590
http://dx.doi.org/10.1038/s10038-021-00958-2

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