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Investigation of measurable residual disease in acute myeloid leukemia by DNA methylation patterns
Assessment of measurable residual disease (MRD) upon treatment of acute myeloid leukemia (AML) remains challenging. It is usually addressed by highly sensitive PCR- or sequencing-based screening of specific mutations, or by multiparametric flow cytometry. However, not all patients have suitable muta...
Autores principales: | Božić, Tanja, Kuo, Chao-Chung, Hapala, Jan, Franzen, Julia, Eipel, Monika, Platzbecker, Uwe, Kirschner, Martin, Beier, Fabian, Jost, Edgar, Thiede, Christian, Wagner, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727289/ https://www.ncbi.nlm.nih.gov/pubmed/34131280 http://dx.doi.org/10.1038/s41375-021-01316-z |
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