Preclinical evaluation of eltrombopag in a PDX model of myelodysplastic syndromes

Preclinical research of myelodysplastic syndromes (MDSs) is hampered by a lack of feasible disease models. Previously, we have established a robust patient-derived xenograft (PDX) model for MDS. Here we demonstrate for the first time that this model is applicable as a preclinical platform to address...

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Detalles Bibliográficos
Autores principales: Schmitt, Nanni, Jann, Johann-Christoph, Altrock, Eva, Flach, Johanna, Danner, Justine, Uhlig, Stefanie, Streuer, Alexander, Knaflic, Antje, Riabov, Vladimir, Xu, Qingyu, Mehralivand, Arwin, Palme, Iris, Nowak, Verena, Obländer, Julia, Weimer, Nadine, Haselmann, Verena, Jawhar, Ahmed, Darwich, Ali, Weis, Cleo-Aron, Marx, Alexander, Steiner, Laurenz, Jawhar, Mohamad, Metzgeroth, Georgia, Boch, Tobias, Nolte, Florian, Hofmann, Wolf-Karsten, Nowak, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727300/
https://www.ncbi.nlm.nih.gov/pubmed/34172896
http://dx.doi.org/10.1038/s41375-021-01327-w

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