Cargando…

SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2

Detalles Bibliográficos
Autores principales: Wu, Leyun, Zhou, Liping, Mo, Mengxia, Liu, Tingting, Wu, Chengkun, Gong, Chunye, Lu, Kai, Gong, Likun, Zhu, Weiliang, Xu, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727475/
https://www.ncbi.nlm.nih.gov/pubmed/34987150
http://dx.doi.org/10.1038/s41392-021-00863-2
_version_ 1784626538060185600
author Wu, Leyun
Zhou, Liping
Mo, Mengxia
Liu, Tingting
Wu, Chengkun
Gong, Chunye
Lu, Kai
Gong, Likun
Zhu, Weiliang
Xu, Zhijian
author_facet Wu, Leyun
Zhou, Liping
Mo, Mengxia
Liu, Tingting
Wu, Chengkun
Gong, Chunye
Lu, Kai
Gong, Likun
Zhu, Weiliang
Xu, Zhijian
author_sort Wu, Leyun
collection PubMed
description
format Online
Article
Text
id pubmed-8727475
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-87274752022-01-05 SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2 Wu, Leyun Zhou, Liping Mo, Mengxia Liu, Tingting Wu, Chengkun Gong, Chunye Lu, Kai Gong, Likun Zhu, Weiliang Xu, Zhijian Signal Transduct Target Ther Letter Nature Publishing Group UK 2022-01-05 /pmc/articles/PMC8727475/ /pubmed/34987150 http://dx.doi.org/10.1038/s41392-021-00863-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Letter
Wu, Leyun
Zhou, Liping
Mo, Mengxia
Liu, Tingting
Wu, Chengkun
Gong, Chunye
Lu, Kai
Gong, Likun
Zhu, Weiliang
Xu, Zhijian
SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2
title SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2
title_full SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2
title_fullStr SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2
title_full_unstemmed SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2
title_short SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2
title_sort sars-cov-2 omicron rbd shows weaker binding affinity than the currently dominant delta variant to human ace2
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727475/
https://www.ncbi.nlm.nih.gov/pubmed/34987150
http://dx.doi.org/10.1038/s41392-021-00863-2
work_keys_str_mv AT wuleyun sarscov2omicronrbdshowsweakerbindingaffinitythanthecurrentlydominantdeltavarianttohumanace2
AT zhouliping sarscov2omicronrbdshowsweakerbindingaffinitythanthecurrentlydominantdeltavarianttohumanace2
AT momengxia sarscov2omicronrbdshowsweakerbindingaffinitythanthecurrentlydominantdeltavarianttohumanace2
AT liutingting sarscov2omicronrbdshowsweakerbindingaffinitythanthecurrentlydominantdeltavarianttohumanace2
AT wuchengkun sarscov2omicronrbdshowsweakerbindingaffinitythanthecurrentlydominantdeltavarianttohumanace2
AT gongchunye sarscov2omicronrbdshowsweakerbindingaffinitythanthecurrentlydominantdeltavarianttohumanace2
AT lukai sarscov2omicronrbdshowsweakerbindingaffinitythanthecurrentlydominantdeltavarianttohumanace2
AT gonglikun sarscov2omicronrbdshowsweakerbindingaffinitythanthecurrentlydominantdeltavarianttohumanace2
AT zhuweiliang sarscov2omicronrbdshowsweakerbindingaffinitythanthecurrentlydominantdeltavarianttohumanace2
AT xuzhijian sarscov2omicronrbdshowsweakerbindingaffinitythanthecurrentlydominantdeltavarianttohumanace2