25-Hydroxyvitamin D potentializes extracellular cathelicidin release from human PBMC stimulated ex vivo with either bacterial (LPS) or viral (P: IC) mimetics

Human cathelicidin refers to the cationic antimicrobial peptide hCAP18/LL-37. LL-37 is formed by cleavage of the propeptide hCAP18 coded by the CAMP gene. The active form of vitamin D, 1,25-dihydroxyvitamin D (1,25(OH)D), has been shown to induce the CAMP gene expression through promoter activation....

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Detalles Bibliográficos
Autores principales: Aldekwer, Sahar, Goncalves-Mendes, Nicolas, Bingula, Rea, Martinroche, Guillaume, Lanchais, Kassandra, Rougé, Stéphanie, Farges, Marie-Chantal, Rossary, Adrien, Diab-Assaf, Mona, Vasson, Marie-Paule, Talvas, Jérémie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727486/
https://www.ncbi.nlm.nih.gov/pubmed/34985728
http://dx.doi.org/10.1007/s13105-021-00868-z

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