Optimization of miR-22 expression cassette for rAAV delivery on diabetes

MicroRNA-22 (miR-22) was suggested to be important for type 2 diabetes but its functions for this disease remained unclear. Recombinant adeno-associated virus (rAAV)-mediated miR delivery is a powerful approach to study miR functions in vivo, however, the overexpression of miR-22 by rAAV remains cha...

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Detalles Bibliográficos
Autores principales: Yang, Li, Du, Wenya, Zheng, Zhaoyue, Wang, Li, Xiao, Lin, Yang, Qingzhe, Hao, Qiukui, Zhou, Jiao, Du, Jintao, Li, Jun, Valencia, C. Alexander, Dong, Birong, Chow, Hoi Yee, Fu, Xianghui, Dong, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727650/
https://www.ncbi.nlm.nih.gov/pubmed/34984525
http://dx.doi.org/10.1186/s43556-021-00063-y

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