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Practice patterns regarding regional corticosteroid treatment in noninfectious Uveitis: a survey study

BACKGROUND: Regional corticosteroid therapy for noninfectious uveitis is well-established but usage patterns have not been studied extensively. This study aims to assess practice patterns of retina and uveitis specialists regarding their preferences on the use of local corticosteroid therapy. METHOD...

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Autores principales: McHarg, Matthew, Young, LeAnne, Kesav, Natasha, Yakin, Mehmet, Sen, H. Nida, Kodati, Shilpa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727651/
https://www.ncbi.nlm.nih.gov/pubmed/34982279
http://dx.doi.org/10.1186/s12348-021-00281-z
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author McHarg, Matthew
Young, LeAnne
Kesav, Natasha
Yakin, Mehmet
Sen, H. Nida
Kodati, Shilpa
author_facet McHarg, Matthew
Young, LeAnne
Kesav, Natasha
Yakin, Mehmet
Sen, H. Nida
Kodati, Shilpa
author_sort McHarg, Matthew
collection PubMed
description BACKGROUND: Regional corticosteroid therapy for noninfectious uveitis is well-established but usage patterns have not been studied extensively. This study aims to assess practice patterns of retina and uveitis specialists regarding their preferences on the use of local corticosteroid therapy. METHODS: A 13-question survey was developed regarding the practice patterns of regional corticosteroid use in specific situations and populations. The survey was distributed to both the American Uveitis Society and Macula Society. RESULTS: Responses from 87 ophthalmologists were analyzed. The two most commonly used drugs were the dexamethasone intravitreal implant (Ozurdex®) and posterior sub-tenon’s triamcinolone (also known as posterior sub-Tenon’s Kenalog, or PSTK). Regional corticosteroids were used more frequently as first-line treatment in more than half of posterior uveitis cases when compared to anterior uveitis (39.1–46.0% vs 10.3%, respectively). Respondents were more willing to use regional corticosteroids in more than half of unilateral uveitis cases than in bilateral cases (54.7% vs 18.6%, respectively). A majority of respondents (67.1%) stated that they would avoid using regional corticosteroids in patients under 8 years old. CONCLUSIONS: Our results demonstrate more frequent regional corticosteroid use in posterior segment uveitis, unilateral cases, and avoidance in younger pediatric patients. Overall, the variability in these responses highlights the need for guidelines regarding regional corticosteroid use. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12348-021-00281-z.
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spelling pubmed-87276512022-01-18 Practice patterns regarding regional corticosteroid treatment in noninfectious Uveitis: a survey study McHarg, Matthew Young, LeAnne Kesav, Natasha Yakin, Mehmet Sen, H. Nida Kodati, Shilpa J Ophthalmic Inflamm Infect Original Research BACKGROUND: Regional corticosteroid therapy for noninfectious uveitis is well-established but usage patterns have not been studied extensively. This study aims to assess practice patterns of retina and uveitis specialists regarding their preferences on the use of local corticosteroid therapy. METHODS: A 13-question survey was developed regarding the practice patterns of regional corticosteroid use in specific situations and populations. The survey was distributed to both the American Uveitis Society and Macula Society. RESULTS: Responses from 87 ophthalmologists were analyzed. The two most commonly used drugs were the dexamethasone intravitreal implant (Ozurdex®) and posterior sub-tenon’s triamcinolone (also known as posterior sub-Tenon’s Kenalog, or PSTK). Regional corticosteroids were used more frequently as first-line treatment in more than half of posterior uveitis cases when compared to anterior uveitis (39.1–46.0% vs 10.3%, respectively). Respondents were more willing to use regional corticosteroids in more than half of unilateral uveitis cases than in bilateral cases (54.7% vs 18.6%, respectively). A majority of respondents (67.1%) stated that they would avoid using regional corticosteroids in patients under 8 years old. CONCLUSIONS: Our results demonstrate more frequent regional corticosteroid use in posterior segment uveitis, unilateral cases, and avoidance in younger pediatric patients. Overall, the variability in these responses highlights the need for guidelines regarding regional corticosteroid use. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12348-021-00281-z. Springer Berlin Heidelberg 2022-01-04 /pmc/articles/PMC8727651/ /pubmed/34982279 http://dx.doi.org/10.1186/s12348-021-00281-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Research
McHarg, Matthew
Young, LeAnne
Kesav, Natasha
Yakin, Mehmet
Sen, H. Nida
Kodati, Shilpa
Practice patterns regarding regional corticosteroid treatment in noninfectious Uveitis: a survey study
title Practice patterns regarding regional corticosteroid treatment in noninfectious Uveitis: a survey study
title_full Practice patterns regarding regional corticosteroid treatment in noninfectious Uveitis: a survey study
title_fullStr Practice patterns regarding regional corticosteroid treatment in noninfectious Uveitis: a survey study
title_full_unstemmed Practice patterns regarding regional corticosteroid treatment in noninfectious Uveitis: a survey study
title_short Practice patterns regarding regional corticosteroid treatment in noninfectious Uveitis: a survey study
title_sort practice patterns regarding regional corticosteroid treatment in noninfectious uveitis: a survey study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727651/
https://www.ncbi.nlm.nih.gov/pubmed/34982279
http://dx.doi.org/10.1186/s12348-021-00281-z
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