Cargando…

Degradation of Components of the Lpt Transenvelope Machinery Reveals LPS-Dependent Lpt Complex Stability in Escherichia coli

Lipopolysaccharide (LPS) is a peculiar component of the outer membrane (OM) of many Gram-negative bacteria that renders these bacteria highly impermeable to many toxic molecules, including antibiotics. LPS is assembled at the OM by a dedicated intermembrane transport system, the Lpt (LPS transport)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martorana, Alessandra M., Moura, Elisabete C. C. M., Sperandeo, Paola, Di Vincenzo, Flavia, Liang, Xiaofei, Toone, Eric, Zhou, Pei, Polissi, Alessandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727689/ https://www.ncbi.nlm.nih.gov/pubmed/35004843 http://dx.doi.org/10.3389/fmolb.2021.758228

Ejemplares similares

Suppressor Mutations in LptF Bypass Essentiality of LptC by Forming a Six-Protein Transenvelope Bridge That Efficiently Transports Lipopolysaccharide
por: Falchi, Federica A., et al.
Publicado: (2022)

Thanatin Impairs Lipopolysaccharide Transport Complex Assembly by Targeting LptC–LptA Interaction and Decreasing LptA Stability
por: Moura, Elisabete C. C. M., et al.
Publicado: (2020)

The Lipopolysaccharide Export Pathway in Escherichia coli: Structure, Organization and Regulated Assembly of the Lpt Machinery
por: Polissi, Alessandra, et al.
Publicado: (2014)

The lipopolysaccharide-transporter complex LptB(2)FG also displays adenylate kinase activity in vitro dependent on the binding partners LptC/LptA
por: Baeta, Tiago, et al.
Publicado: (2021)

Pseudomonas aeruginosa LptE is crucial for LptD assembly, cell envelope integrity, antibiotic resistance and virulence
por: Lo Sciuto, Alessandra, et al.
Publicado: (2018)

Interaction of lipopolysaccharides at intermolecular sites of the periplasmic Lpt transport assembly
por: Laguri, Cedric, et al.
Publicado: (2017)

The Lack of the Essential LptC Protein in the Trans-Envelope Lipopolysaccharide Transport Machine Is Circumvented by Suppressor Mutations in LptF, an Inner Membrane Component of the Escherichia coli Transporter
por: Benedet, Mattia, et al.
Publicado: (2016)

Identification of a Small Molecule That Inhibits the Interaction of LPS Transporters LptA and LptC
por: Dai, Xiaowei, et al.
Publicado: (2022)

The transmembrane α‐helix of LptC participates in LPS extraction by the LptB(2)FGC transporter
por: Wilson, Andrew, et al.
Publicado: (2022)

LptD depletion disrupts morphological homeostasis and upregulates carbohydrate metabolism in Escherichia coli
por: Frisinger, Frida Svanberg, et al.
Publicado: (2023)

Role of LptD in Resistance to Glutaraldehyde and Pathogenicity in Riemerella anatipestifer
por: Huang, Li, et al.
Publicado: (2019)

Trapped lipopolysaccharide and LptD intermediates reveal lipopolysaccharide translocation steps across the Escherichia coli outer membrane
por: Li, Xuejun, et al.
Publicado: (2015)

Technical Training Seminar: Laser Trackers: the Local Positioning Technology (LPT)
por: Davide Vitè
Publicado: (2005)

Technical Training Seminar: Laser Trackers: the Local Positioning Technology (LPT)
por: Davide Vitè
Publicado: (2005)

Structural basis of lipopolysaccharide extraction by the LptB(2)FGC complex
por: Li, Yanyan, et al.
Publicado: (2019)

Structure and Functional Analysis of LptC, a Conserved Membrane Protein Involved in the Lipopolysaccharide Export Pathway in Escherichia coli
por: Tran, An X., et al.
Publicado: (2010)

Structural and functional insights into the lipopolysaccharide ABC transporter LptB(2)FG
por: Dong, Haohao, et al.
Publicado: (2017)

Constipation and clozapine: a QI project in Leicestershire Partnership NHS Trust, (LPT)
por: Evbuomwam, Ehimwenma, et al.
Publicado: (2021)

Early Molecular Insights into Thanatin Analogues Binding to A. baumannii LptA
por: Oi, Kathryn K., et al.
Publicado: (2023)

LptM promotes oxidative maturation of the lipopolysaccharide translocon by substrate binding mimicry
por: Yang, Yiying, et al.
Publicado: (2023)

Mutational analysis of the essential lipopolysaccharide-transport protein LptH of Pseudomonas aeruginosa to uncover critical oligomerization sites
por: Scala, Romina, et al.
Publicado: (2020)

Dissecting Escherichia coli Outer Membrane Biogenesis Using Differential Proteomics
por: Martorana, Alessandra M., et al.
Publicado: (2014)

Functional characterization of the type I toxin Lpt from Lactobacillus rhamnosus by fluorescence and atomic force microscopy
por: Maggi, Stefano, et al.
Publicado: (2019)

lptG contributes to changes in membrane permeability and the emergence of multidrug hypersusceptibility in a cystic fibrosis isolate of Pseudomonas aeruginosa
por: Harrison, Lucas B., et al.
Publicado: (2019)

Phosphoethanolamine Transferase LptA in Haemophilus ducreyi Modifies Lipid A and Contributes to Human Defensin Resistance In Vitro
por: Trombley, Michael P., et al.
Publicado: (2015)

Lipopolysaccharide is Inserted into the Outer Membrane through An Intramembrane Hole, A Lumen Gate, and the Lateral Opening of LptD
por: Gu, Yinghong, et al.
Publicado: (2015)

LptD is a promising vaccine antigen and potential immunotherapeutic target for protection against Vibrio species infection
por: Zha, Zhenzhong, et al.
Publicado: (2016)

Identification of lptA, lpxE, and lpxO, Three Genes Involved in the Remodeling of Brucella Cell Envelope
por: Conde-Álvarez, Raquel, et al.
Publicado: (2018)

Massive antibody discovery used to probe structure–function relationships of the essential outer membrane protein LptD
por: Storek, Kelly M, et al.
Publicado: (2019)

LptO (PG0027) Is Required for Lipid A 1-Phosphatase Activity in Porphyromonas gingivalis W50
por: Rangarajan, Minnie, et al.
Publicado: (2017)

Non–heat inactivated autologous serum increases accuracy of in vitro CFSE lymphocyte proliferation test (LPT) for nickel
por: de Graaf, Niels P. J., et al.
Publicado: (2020)

Therapeutic efficiency of the APAF‐1 antagonist LPT99 in a rat model of cisplatin‐induced hearing loss
por: Murillo‐Cuesta, Silvia, et al.
Publicado: (2021)

Cryo-EM structures of a LptDE transporter in complex with Pro-macrobodies offer insight into lipopolysaccharide translocation
por: Botte, Mathieu, et al.
Publicado: (2022)

Comparing [(3)H] thymidine LPT and CFSE assay to assess lymphocyte proliferation in beryllium-exposed sarcoidosis patients
por: Ganesan, Nirosha, et al.
Publicado: (2023)

Discovery, characterization, and redesign of potent antimicrobial thanatin orthologs from Chinavia ubica and Murgantia histrionica targeting E. coli LptA
por: Huynh, Kelly, et al.
Publicado: (2023)

Mutations in pmrB Confer Cross-Resistance between the LptD Inhibitor POL7080 and Colistin in Pseudomonas aeruginosa
por: Romano, Keith P., et al.
Publicado: (2019)

Edge-strand of BepA interacts with immature LptD on the β-barrel assembly machine to direct it to on- and off-pathways
por: Miyazaki, Ryoji, et al.
Publicado: (2021)

Editorial: Weak Interactions in Molecular Machinery
por: Isaacson, Rivka L., et al.
Publicado: (2019)

Energy Starvation Induces a Cell Cycle Arrest in Escherichia coli by Triggering Degradation of the DnaA Initiator Protein
por: Charbon, Godefroid, et al.
Publicado: (2021)

Editorial: The DNA Replication Machinery as Therapeutic Targets
por: Gardner, Andrew F., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_34pb2hh61pr6co1j8itiko446a