The key role of gut–liver axis in pyrrolizidine alkaloid-induced hepatotoxicity and enterotoxicity

Pyrrolizidine alkaloids (PAs) are the most common phytotoxins with documented human hepatotoxicity. PAs require metabolic activation by cytochromes P450 to generate toxic intermediates which bind to proteins and form protein adducts, thereby causing cytotoxicity. This study investigated the role of...

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Detalles Bibliográficos
Autores principales: He, Yisheng, Ma, Jiang, Fan, Xiaoyu, Ding, Liang, Ding, Xinxin, Zhang, Qing-Yu, Lin, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727778/
https://www.ncbi.nlm.nih.gov/pubmed/35024309
http://dx.doi.org/10.1016/j.apsb.2021.07.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727778/
https://www.ncbi.nlm.nih.gov/pubmed/35024309
http://dx.doi.org/10.1016/j.apsb.2021.07.013

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