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Deubiquitinase JOSD2 stabilizes YAP/TAZ to promote cholangiocarcinoma progression
Cholangiocarcinoma (CCA) has emerged as an intractable cancer with scanty therapeutic regimens. The aberrant activation of Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are reported to be common in CCA patients. However, the underpinning mechanism remains...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727894/ https://www.ncbi.nlm.nih.gov/pubmed/35024322 http://dx.doi.org/10.1016/j.apsb.2021.04.003 |