Deubiquitinase JOSD2 stabilizes YAP/TAZ to promote cholangiocarcinoma progression

Cholangiocarcinoma (CCA) has emerged as an intractable cancer with scanty therapeutic regimens. The aberrant activation of Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are reported to be common in CCA patients. However, the underpinning mechanism remains...

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Detalles Bibliográficos
Autores principales: Qian, Meijia, Yan, Fangjie, Wang, Weihua, Du, Jiamin, Yuan, Tao, Wu, Ruilin, Zhao, Chenxi, Wang, Jiao, Lu, Jiabin, Zhang, Bo, Lin, Nengming, Dong, Xin, Dai, Xiaoyang, Dong, Xiaowu, Yang, Bo, Zhu, Hong, He, Qiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727894/
https://www.ncbi.nlm.nih.gov/pubmed/35024322
http://dx.doi.org/10.1016/j.apsb.2021.04.003

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