Dual roles of p62/SQSTM1 in the injury and recovery phases of acetaminophen-induced liver injury in mice

Acetaminophen (APAP) overdose can induce liver injury and is the most frequent cause of acute liver failure in the United States. We investigated the role of p62/SQSTM1 (referred to as p62) in APAP-induced liver injury (AILI) in mice. We found that the hepatic protein levels of p62 dramatically incr...

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Detalles Bibliográficos
Autores principales: Qian, Hui, Bai, Qingyun, Yang, Xiao, Akakpo, Jephte Y., Ji, Lili, Yang, Li, Rülicke, Thomas, Zatloukal, Kurt, Jaeschke, Hartmut, Ni, Hong-Min, Ding, Wen-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727897/
https://www.ncbi.nlm.nih.gov/pubmed/35024307
http://dx.doi.org/10.1016/j.apsb.2021.11.010

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