Cargando…

Accumulation of amyloid beta (Aβ) and amyloid precursor protein (APP) in tumors formed by a mouse xenograft model of inflammatory breast cancer

Accumulation of amyloid in breast cancer is a well‐known phenomenon, but only immunoglobulin light‐chain amyloidosis (AL) or transthyretin (TTR) amyloid had been detected in human breast tumor samples previously. We recently reported that another amyloidogenic peptide, amyloid beta (Aβ), is present...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zayas‐Santiago, Astrid, Martínez‐Montemayor, Michelle M., Colón‐Vázquez, Jadier, Ortiz‐Soto, Gabriela, Cirino‐Simonet, Jose G., Inyushin, Mikhail
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727955/ https://www.ncbi.nlm.nih.gov/pubmed/34592066 http://dx.doi.org/10.1002/2211-5463.13308

Ejemplares similares

Accumulation of Innate Amyloid Beta Peptide in Glioblastoma Tumors
por: Kucheryavykh, Lilia Y., et al.
Publicado: (2019)

Accumulation of amyloid beta in human glioblastomas
por: Zayas‐Santiago, A., et al.
Publicado: (2020)

On the Role of Platelet-Generated Amyloid Beta Peptides in Certain Amyloidosis Health Complications
por: Inyushin, Mikhail, et al.
Publicado: (2020)

Accumulation of Amyloid Beta (Aβ) Peptide on Blood Vessel Walls in the Damaged Brain after Transient Middle Cerebral Artery Occlusion
por: Martins, Antonio Henrique, et al.
Publicado: (2019)

Amyloid Beta Peptide Is Released during Thrombosis in the Skin
por: Kucheryavykh, Lilia Y., et al.
Publicado: (2018)

Amyloid Precursor Protein (APP) and GABAergic Neurotransmission
por: Tang, Bor Luen
Publicado: (2019)

EDEM1 Regulates Amyloid Precursor Protein (APP) Metabolism and Amyloid-β Production
por: Nowakowska-Gołacka, Jowita, et al.
Publicado: (2021)

β-Amyloid precursor protein (APP) and the human diseases
por: Nguyen, Khue Vu
Publicado: (2019)

Targeting amyloid precursor protein shuttling and processing - long before amyloid beta formation
por: Arbor, Sage
Publicado: (2017)

Role of amyloid precursor protein (APP) in regulation of neuronal genes
por: Nalivaeva, Natalia N.
Publicado: (2015)

Therapeutic Potential of Secreted Amyloid Precursor Protein APPsα
por: Mockett, Bruce G., et al.
Publicado: (2017)

The amyloid precursor protein: beyond amyloid
por: Zheng, Hui, et al.
Publicado: (2006)

ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular amyloid-β accumulation
por: Edgar, James R., et al.
Publicado: (2015)

Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes
por: Tang, Weihao, et al.
Publicado: (2015)

Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta
por: Lopez Sanchez, M. Isabel G., et al.
Publicado: (2017)

A Bifunctional Anti-Amyloid Blocks Oxidative Stress and the Accumulation of Intraneuronal Amyloid-Beta
por: Hilt, Silvia, et al.
Publicado: (2018)

Extracellular vesicles: where the amyloid precursor protein carboxyl‐terminal fragments accumulate and amyloid‐β oligomerizes
por: Pérez‐González, Rocío, et al.
Publicado: (2020)

Amyloid precursor protein and amyloid precursor-like protein 2 in cancer
por: Pandey, Poomy, et al.
Publicado: (2016)

Analysis of the Overall Structure of the Multi-Domain Amyloid Precursor Protein (APP)
por: Coburger, Ina, et al.
Publicado: (2013)

Molecular Characteristics of Amyloid Precursor Protein (APP) and Its Effects in Cancer
por: Lee, Han Na, et al.
Publicado: (2021)

The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid
por: Tam, Joshua HK, et al.
Publicado: (2014)

Neuroinflammatory Cytokines Induce Amyloid Beta Neurotoxicity through Modulating Amyloid Precursor Protein Levels/Metabolism
por: Alasmari, Fawaz, et al.
Publicado: (2018)

Whole Cigarette Smoke Condensates Induce Accumulation of Amyloid Beta Precursor Protein with Oxidative Stress in Murine Astrocytes
por: Park, Eun-Jung, et al.
Publicado: (2021)

Beta-Secretase 1 Recruits Amyloid-Beta Precursor Protein to ROCK2 Kinase, Resulting in Erroneous Phosphorylation and Beta-Amyloid Plaque Formation
por: Hajdú, István, et al.
Publicado: (2023)

Interactions between amyloid, amyloid precursor protein, and mitochondria
por: Wilkins, Heather M.
Publicado: (2023)

Effects of DDT on Amyloid Precursor Protein Levels and Amyloid Beta Pathology: Mechanistic Links to Alzheimer’s Disease Risk
por: Eid, Aseel, et al.
Publicado: (2022)

Tissue Transparency In Vivo
por: Inyushin, Mikhail, et al.
Publicado: (2019)

Results of Beta Secretase-Inhibitor Clinical Trials Support Amyloid Precursor Protein-Independent Generation of Beta Amyloid in Sporadic Alzheimer’s Disease
por: Volloch, Vladimir, et al.
Publicado: (2018)

Icaritin, an inhibitor of beta-site amyloid cleaving enzyme-1, inhibits secretion of amyloid precursor protein in APP-PS1-HEK293 cells by impeding the amyloidogenic pathway
por: Feng, Fei, et al.
Publicado: (2019)

The Alzheimer Amyloid Precursor Protein (APP) and Fe65, an APP-Binding Protein, Regulate Cell Movement
por: Sabo, Shasta L., et al.
Publicado: (2001)

Phosphorylation of the amyloid precursor protein (APP) at Ser-675 promotes APP processing involving meprin β
por: Menon, Preeti Kumaran, et al.
Publicado: (2019)

Nucleofection of Rat Pheochromocytoma PC-12 Cells with Human Mutated Beta-Amyloid Precursor Protein Gene (APP-sw) Leads to Reduced Viability, Autophagy-Like Process, and Increased Expression and Secretion of Beta Amyloid
por: Pająk, Beata, et al.
Publicado: (2015)

The type of Aβ-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid β-peptide (APP48) transgenic mice
por: Rijal Upadhaya, Ajeet, et al.
Publicado: (2013)

Activation of Ras-ERK Signaling and GSK-3 by Amyloid Precursor Protein and Amyloid Beta Facilitates Neurodegeneration in Alzheimer’s Disease
por: Kirouac, Lisa, et al.
Publicado: (2017)

Nicotinamide Reduces Amyloid Precursor Protein and Presenilin 1 in Brain Tissues of Amyloid Beta-Tail Vein Injected Mice
por: Kim, Eun Jin, et al.
Publicado: (2017)

Studying the Progression of Amyloid Pathology and Its Therapy Using Translational Longitudinal Model of Accumulation and Distribution of Amyloid Beta
por: Karelina, Tatiana, et al.
Publicado: (2017)

Amyloid beta accumulations and enhanced neuronal differentiation in cerebral organoids of Dutch-type cerebral amyloid angiopathy patients
por: Daoutsali, Elena, et al.
Publicado: (2023)

Effects of Gene Imbalance on Amyloid Precursor Protein [APP] Expression in Grafts and Recipient Cortex
por: Hohmann, C. F., et al.
Publicado: (1992)

Independent Relationship between Amyloid Precursor Protein (APP) Dimerization and γ-Secretase Processivity
por: Jung, Joo In, et al.
Publicado: (2014)

Amyloid Precursor Protein (APP) Affects Global Protein Synthesis in Dividing Human Cells
por: Sobol, Anna, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_6gcappo89pttr8pjjsb671d05r