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Phenotyping of multiple sclerosis lesions according to innate immune cell activation using 18 kDa translocator protein-PET

Chronic active lesions are promotors of neurodegeneration and disease progression in multiple sclerosis. They harbour a dense rim of activated innate immune cells at the lesion edge, which promotes lesion growth and thereby induces damage. Conventional MRI is of limited help in identifying the chron...

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Detalles Bibliográficos
Autores principales: Nylund, Marjo, Sucksdorff, Marcus, Matilainen, Markus, Polvinen, Eero, Tuisku, Jouni, Airas, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727984/
https://www.ncbi.nlm.nih.gov/pubmed/34993478
http://dx.doi.org/10.1093/braincomms/fcab301