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FrAnTK: a Frequency-based Analysis ToolKit for efficient exploration of allele sharing patterns in present-day and ancient genomic datasets
Present-day and ancient population genomic studies from different study organisms have rapidly become accessible to diverse research groups worldwide. Unfortunately, as datasets and analyses become more complex, researchers with less computational experience often miss their chance to analyze their...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727993/ https://www.ncbi.nlm.nih.gov/pubmed/34791203 http://dx.doi.org/10.1093/g3journal/jkab357 |
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author | Moreno-Mayar, J Víctor |
author_facet | Moreno-Mayar, J Víctor |
author_sort | Moreno-Mayar, J Víctor |
collection | PubMed |
description | Present-day and ancient population genomic studies from different study organisms have rapidly become accessible to diverse research groups worldwide. Unfortunately, as datasets and analyses become more complex, researchers with less computational experience often miss their chance to analyze their own data. We introduce FrAnTK, a user-friendly toolkit for computation and visualization of allele frequency-based statistics in ancient and present-day genome variation datasets. We provide fast, memory-efficient tools that allow the user to go from sequencing data to complex exploratory analyses and visual representations with minimal data manipulation. Its simple usage and low computational requirements make FrAnTK ideal for users that are less familiar with computer programming carrying out large-scale population studies. |
format | Online Article Text |
id | pubmed-8727993 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-87279932022-01-05 FrAnTK: a Frequency-based Analysis ToolKit for efficient exploration of allele sharing patterns in present-day and ancient genomic datasets Moreno-Mayar, J Víctor G3 (Bethesda) Software and Data Resources Present-day and ancient population genomic studies from different study organisms have rapidly become accessible to diverse research groups worldwide. Unfortunately, as datasets and analyses become more complex, researchers with less computational experience often miss their chance to analyze their own data. We introduce FrAnTK, a user-friendly toolkit for computation and visualization of allele frequency-based statistics in ancient and present-day genome variation datasets. We provide fast, memory-efficient tools that allow the user to go from sequencing data to complex exploratory analyses and visual representations with minimal data manipulation. Its simple usage and low computational requirements make FrAnTK ideal for users that are less familiar with computer programming carrying out large-scale population studies. Oxford University Press 2021-10-13 /pmc/articles/PMC8727993/ /pubmed/34791203 http://dx.doi.org/10.1093/g3journal/jkab357 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Genetics Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Software and Data Resources Moreno-Mayar, J Víctor FrAnTK: a Frequency-based Analysis ToolKit for efficient exploration of allele sharing patterns in present-day and ancient genomic datasets |
title | FrAnTK: a Frequency-based Analysis ToolKit for efficient exploration of allele sharing patterns in present-day and ancient genomic datasets |
title_full | FrAnTK: a Frequency-based Analysis ToolKit for efficient exploration of allele sharing patterns in present-day and ancient genomic datasets |
title_fullStr | FrAnTK: a Frequency-based Analysis ToolKit for efficient exploration of allele sharing patterns in present-day and ancient genomic datasets |
title_full_unstemmed | FrAnTK: a Frequency-based Analysis ToolKit for efficient exploration of allele sharing patterns in present-day and ancient genomic datasets |
title_short | FrAnTK: a Frequency-based Analysis ToolKit for efficient exploration of allele sharing patterns in present-day and ancient genomic datasets |
title_sort | frantk: a frequency-based analysis toolkit for efficient exploration of allele sharing patterns in present-day and ancient genomic datasets |
topic | Software and Data Resources |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727993/ https://www.ncbi.nlm.nih.gov/pubmed/34791203 http://dx.doi.org/10.1093/g3journal/jkab357 |
work_keys_str_mv | AT morenomayarjvictor frantkafrequencybasedanalysistoolkitforefficientexplorationofallelesharingpatternsinpresentdayandancientgenomicdatasets |