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Impact of opioids on P2Y(12) receptor inhibition in patients with ST-elevation myocardial infarction who are pre-treated with crushed ticagrelor: Opioids aNd crushed Ticagrelor In Myocardial infarction Evaluation (ON-TIME 3) trial
AIMS: Platelet inhibition induced by P2Y(12) receptor antagonists in patients with ST-elevation myocardial infarction (STEMI) can be affected by concomitant use of opioids. The aim of this trial was to examine the effect of intravenous (iv) acetaminophen compared with iv fentanyl on P2Y(12) receptor...
Autores principales: | Tavenier, Anne H, Hermanides, Renicus S, Ottervanger, Jan Paul, Tolsma, Rudolf, van Beurden, Antony, Slingerland, Robbert Jan, ter Horst, Peter G J, Gosselink, A T Marcel, Dambrink, Jan-Henk E, van Leeuwen, Maarten A H, Roolvink, Vincent, Kedhi, Elvin, Klungel, Olaf H, Belitser, Svetlana V, Angiolillo, Dominick J, Pustjens, Tobias, Rasoul, Saman, Gho, Ben, Stein, Mera, Ruiters, Lex, van ‘t Hof, Arnoud W J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728016/ https://www.ncbi.nlm.nih.gov/pubmed/32730628 http://dx.doi.org/10.1093/ehjcvp/pvaa095 |
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