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Ayurvedic management in limb girdle muscular dystrophy – A case report

Limb girdle muscular dystrophy (LGMD) is a type of Muscular dystrophy (MD), heterogeneous devastating complex genetic disorders causing progressive weakness and degeneration of muscles. LGMD is hereditary autosomal diseases characterized by weak and wasteful limb girdle muscles. The available manage...

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Autores principales: Rajoria, Kshipra, Singh, Sarvesh Kumar, Dadhich, Suman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728082/
https://www.ncbi.nlm.nih.gov/pubmed/34961685
http://dx.doi.org/10.1016/j.jaim.2021.07.002
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author Rajoria, Kshipra
Singh, Sarvesh Kumar
Dadhich, Suman
author_facet Rajoria, Kshipra
Singh, Sarvesh Kumar
Dadhich, Suman
author_sort Rajoria, Kshipra
collection PubMed
description Limb girdle muscular dystrophy (LGMD) is a type of Muscular dystrophy (MD), heterogeneous devastating complex genetic disorders causing progressive weakness and degeneration of muscles. LGMD is hereditary autosomal diseases characterized by weak and wasteful limb girdle muscles. The available management of LGMD in biomedicine is unsatisfactory. Here we present a case of LGMD managed with combinations of Ayurvedic oral medicines and Panchakarma procedures. The Ayurvedic diagnosis of the condition was considered as Mansagata Vata (∼neuromuscular diseases), a type of Vatavyadhi (∼neuromusculo skeleton disorders). The patient was treated with Shalishashtika Pinda Swedana and Mustadi Yapana Basti for the duration of 16 days along with following Ayurvedic oral medicines: Yograj Guggulu 500 mg with 40 ml Dashamoola Kwatha, Ekangaveera Rasa 125 mg with honey, a combination of Ashwagandha Churna -2g, Satavari Churna - 2g, and Sankha Bhasma 500 mg with milk, Narsinha Churna- 3g and Ashwagandhavleha- 5g with milk. All medicines were given twice a day. Patient's condition was assessed for symptoms of pain, walking distance, power and reflexes of both upper and lower limb and psedohypertrophy of both calf muscles. Serum Creatine Phoshphokinase (S.CPK) level and electromyography (EMG) were also measured. There was symptomatic improvement in the patient's condition and reduction in S.CPK level. The study suggests that LGMD can be satisfactorily managed with Ayurvedic oral medicines and Panchakarma therapy.
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spelling pubmed-87280822022-01-11 Ayurvedic management in limb girdle muscular dystrophy – A case report Rajoria, Kshipra Singh, Sarvesh Kumar Dadhich, Suman J Ayurveda Integr Med Case Report Limb girdle muscular dystrophy (LGMD) is a type of Muscular dystrophy (MD), heterogeneous devastating complex genetic disorders causing progressive weakness and degeneration of muscles. LGMD is hereditary autosomal diseases characterized by weak and wasteful limb girdle muscles. The available management of LGMD in biomedicine is unsatisfactory. Here we present a case of LGMD managed with combinations of Ayurvedic oral medicines and Panchakarma procedures. The Ayurvedic diagnosis of the condition was considered as Mansagata Vata (∼neuromuscular diseases), a type of Vatavyadhi (∼neuromusculo skeleton disorders). The patient was treated with Shalishashtika Pinda Swedana and Mustadi Yapana Basti for the duration of 16 days along with following Ayurvedic oral medicines: Yograj Guggulu 500 mg with 40 ml Dashamoola Kwatha, Ekangaveera Rasa 125 mg with honey, a combination of Ashwagandha Churna -2g, Satavari Churna - 2g, and Sankha Bhasma 500 mg with milk, Narsinha Churna- 3g and Ashwagandhavleha- 5g with milk. All medicines were given twice a day. Patient's condition was assessed for symptoms of pain, walking distance, power and reflexes of both upper and lower limb and psedohypertrophy of both calf muscles. Serum Creatine Phoshphokinase (S.CPK) level and electromyography (EMG) were also measured. There was symptomatic improvement in the patient's condition and reduction in S.CPK level. The study suggests that LGMD can be satisfactorily managed with Ayurvedic oral medicines and Panchakarma therapy. Elsevier 2022 2021-12-24 /pmc/articles/PMC8728082/ /pubmed/34961685 http://dx.doi.org/10.1016/j.jaim.2021.07.002 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Rajoria, Kshipra
Singh, Sarvesh Kumar
Dadhich, Suman
Ayurvedic management in limb girdle muscular dystrophy – A case report
title Ayurvedic management in limb girdle muscular dystrophy – A case report
title_full Ayurvedic management in limb girdle muscular dystrophy – A case report
title_fullStr Ayurvedic management in limb girdle muscular dystrophy – A case report
title_full_unstemmed Ayurvedic management in limb girdle muscular dystrophy – A case report
title_short Ayurvedic management in limb girdle muscular dystrophy – A case report
title_sort ayurvedic management in limb girdle muscular dystrophy – a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728082/
https://www.ncbi.nlm.nih.gov/pubmed/34961685
http://dx.doi.org/10.1016/j.jaim.2021.07.002
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