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mBodyMap: a curated database for microbes across human body and their associations with health and diseases

mBodyMap is a curated database for microbes across the human body and their associations with health and diseases. Its primary aim is to promote the reusability of human-associated metagenomic data and assist with the identification of disease-associated microbes by consistently annotating the micro...

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Autores principales: Jin, Hanbo, Hu, Guoru, Sun, Chuqing, Duan, Yiqian, Zhang, Zhenmo, Liu, Zhi, Zhao, Xing-Ming, Chen, Wei-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728210/
https://www.ncbi.nlm.nih.gov/pubmed/34718713
http://dx.doi.org/10.1093/nar/gkab973
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author Jin, Hanbo
Hu, Guoru
Sun, Chuqing
Duan, Yiqian
Zhang, Zhenmo
Liu, Zhi
Zhao, Xing-Ming
Chen, Wei-Hua
author_facet Jin, Hanbo
Hu, Guoru
Sun, Chuqing
Duan, Yiqian
Zhang, Zhenmo
Liu, Zhi
Zhao, Xing-Ming
Chen, Wei-Hua
author_sort Jin, Hanbo
collection PubMed
description mBodyMap is a curated database for microbes across the human body and their associations with health and diseases. Its primary aim is to promote the reusability of human-associated metagenomic data and assist with the identification of disease-associated microbes by consistently annotating the microbial contents of collected samples using state-of-the-art toolsets and manually curating the meta-data of corresponding human hosts. mBodyMap organizes collected samples based on their association with human diseases and body sites to enable cross-dataset integration and comparison. To help users find microbes of interest and visualize and compare their distributions and abundances/prevalence within different body sites and various diseases, the mBodyMap database is equipped with an intuitive interface and extensive graphical representations of the collected data. So far, it contains a total of 63 148 runs, including 14 401 metagenomes and 48 747 amplicons related to health and 56 human diseases, from within 22 human body sites across 136 projects. Also available in the database are pre-computed abundances and prevalence of 6247 species (belonging to 1645 genera) stratified by body sites and diseases. mBodyMap can be accessed at: https://mbodymap.microbiome.cloud.
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spelling pubmed-87282102022-01-05 mBodyMap: a curated database for microbes across human body and their associations with health and diseases Jin, Hanbo Hu, Guoru Sun, Chuqing Duan, Yiqian Zhang, Zhenmo Liu, Zhi Zhao, Xing-Ming Chen, Wei-Hua Nucleic Acids Res Database Issue mBodyMap is a curated database for microbes across the human body and their associations with health and diseases. Its primary aim is to promote the reusability of human-associated metagenomic data and assist with the identification of disease-associated microbes by consistently annotating the microbial contents of collected samples using state-of-the-art toolsets and manually curating the meta-data of corresponding human hosts. mBodyMap organizes collected samples based on their association with human diseases and body sites to enable cross-dataset integration and comparison. To help users find microbes of interest and visualize and compare their distributions and abundances/prevalence within different body sites and various diseases, the mBodyMap database is equipped with an intuitive interface and extensive graphical representations of the collected data. So far, it contains a total of 63 148 runs, including 14 401 metagenomes and 48 747 amplicons related to health and 56 human diseases, from within 22 human body sites across 136 projects. Also available in the database are pre-computed abundances and prevalence of 6247 species (belonging to 1645 genera) stratified by body sites and diseases. mBodyMap can be accessed at: https://mbodymap.microbiome.cloud. Oxford University Press 2021-10-28 /pmc/articles/PMC8728210/ /pubmed/34718713 http://dx.doi.org/10.1093/nar/gkab973 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Database Issue
Jin, Hanbo
Hu, Guoru
Sun, Chuqing
Duan, Yiqian
Zhang, Zhenmo
Liu, Zhi
Zhao, Xing-Ming
Chen, Wei-Hua
mBodyMap: a curated database for microbes across human body and their associations with health and diseases
title mBodyMap: a curated database for microbes across human body and their associations with health and diseases
title_full mBodyMap: a curated database for microbes across human body and their associations with health and diseases
title_fullStr mBodyMap: a curated database for microbes across human body and their associations with health and diseases
title_full_unstemmed mBodyMap: a curated database for microbes across human body and their associations with health and diseases
title_short mBodyMap: a curated database for microbes across human body and their associations with health and diseases
title_sort mbodymap: a curated database for microbes across human body and their associations with health and diseases
topic Database Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728210/
https://www.ncbi.nlm.nih.gov/pubmed/34718713
http://dx.doi.org/10.1093/nar/gkab973
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