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The IntAct database: efficient access to fine-grained molecular interaction data
The IntAct molecular interaction database (https://www.ebi.ac.uk/intact) is a curated resource of molecular interactions, derived from the scientific literature and from direct data depositions. As of August 2021, IntAct provides more than one million binary interactions, curated by twelve global pa...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728211/ https://www.ncbi.nlm.nih.gov/pubmed/34761267 http://dx.doi.org/10.1093/nar/gkab1006 |
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| author | del Toro, Noemi Shrivastava, Anjali Ragueneau, Eliot Meldal, Birgit Combe, Colin Barrera, Elisabet Perfetto, Livia How, Karyn Ratan, Prashansa Shirodkar, Gautam Lu, Odilia Mészáros, Bálint Watkins, Xavier Pundir, Sangya Licata, Luana Iannuccelli, Marta Pellegrini, Matteo Martin, Maria Jesus Panni, Simona Duesbury, Margaret Vallet, Sylvain D Rappsilber, Juri Ricard-Blum, Sylvie Cesareni, Gianni Salwinski, Lukasz Orchard, Sandra Porras, Pablo Panneerselvam, Kalpana Hermjakob, Henning |
| author_facet | del Toro, Noemi Shrivastava, Anjali Ragueneau, Eliot Meldal, Birgit Combe, Colin Barrera, Elisabet Perfetto, Livia How, Karyn Ratan, Prashansa Shirodkar, Gautam Lu, Odilia Mészáros, Bálint Watkins, Xavier Pundir, Sangya Licata, Luana Iannuccelli, Marta Pellegrini, Matteo Martin, Maria Jesus Panni, Simona Duesbury, Margaret Vallet, Sylvain D Rappsilber, Juri Ricard-Blum, Sylvie Cesareni, Gianni Salwinski, Lukasz Orchard, Sandra Porras, Pablo Panneerselvam, Kalpana Hermjakob, Henning |
| author_sort | del Toro, Noemi |
| collection | PubMed |
| description | The IntAct molecular interaction database (https://www.ebi.ac.uk/intact) is a curated resource of molecular interactions, derived from the scientific literature and from direct data depositions. As of August 2021, IntAct provides more than one million binary interactions, curated by twelve global partners of the International Molecular Exchange consortium, for which the IntAct database provides a shared curation and dissemination platform. The IMEx curation policy has always emphasised a fine-grained data and curation model, aiming to capture the relevant experimental detail essential for the interpretation of the provided molecular interaction data. Here, we present recent curation focus and progress, as well as a completely redeveloped website which presents IntAct data in a much more user-friendly and detailed way. |
| format | Online Article Text |
| id | pubmed-8728211 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Oxford University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-87282112022-01-05 The IntAct database: efficient access to fine-grained molecular interaction data del Toro, Noemi Shrivastava, Anjali Ragueneau, Eliot Meldal, Birgit Combe, Colin Barrera, Elisabet Perfetto, Livia How, Karyn Ratan, Prashansa Shirodkar, Gautam Lu, Odilia Mészáros, Bálint Watkins, Xavier Pundir, Sangya Licata, Luana Iannuccelli, Marta Pellegrini, Matteo Martin, Maria Jesus Panni, Simona Duesbury, Margaret Vallet, Sylvain D Rappsilber, Juri Ricard-Blum, Sylvie Cesareni, Gianni Salwinski, Lukasz Orchard, Sandra Porras, Pablo Panneerselvam, Kalpana Hermjakob, Henning Nucleic Acids Res Database Issue The IntAct molecular interaction database (https://www.ebi.ac.uk/intact) is a curated resource of molecular interactions, derived from the scientific literature and from direct data depositions. As of August 2021, IntAct provides more than one million binary interactions, curated by twelve global partners of the International Molecular Exchange consortium, for which the IntAct database provides a shared curation and dissemination platform. The IMEx curation policy has always emphasised a fine-grained data and curation model, aiming to capture the relevant experimental detail essential for the interpretation of the provided molecular interaction data. Here, we present recent curation focus and progress, as well as a completely redeveloped website which presents IntAct data in a much more user-friendly and detailed way. Oxford University Press 2021-11-11 /pmc/articles/PMC8728211/ /pubmed/34761267 http://dx.doi.org/10.1093/nar/gkab1006 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Database Issue del Toro, Noemi Shrivastava, Anjali Ragueneau, Eliot Meldal, Birgit Combe, Colin Barrera, Elisabet Perfetto, Livia How, Karyn Ratan, Prashansa Shirodkar, Gautam Lu, Odilia Mészáros, Bálint Watkins, Xavier Pundir, Sangya Licata, Luana Iannuccelli, Marta Pellegrini, Matteo Martin, Maria Jesus Panni, Simona Duesbury, Margaret Vallet, Sylvain D Rappsilber, Juri Ricard-Blum, Sylvie Cesareni, Gianni Salwinski, Lukasz Orchard, Sandra Porras, Pablo Panneerselvam, Kalpana Hermjakob, Henning The IntAct database: efficient access to fine-grained molecular interaction data |
| title | The IntAct database: efficient access to fine-grained molecular interaction data |
| title_full | The IntAct database: efficient access to fine-grained molecular interaction data |
| title_fullStr | The IntAct database: efficient access to fine-grained molecular interaction data |
| title_full_unstemmed | The IntAct database: efficient access to fine-grained molecular interaction data |
| title_short | The IntAct database: efficient access to fine-grained molecular interaction data |
| title_sort | intact database: efficient access to fine-grained molecular interaction data |
| topic | Database Issue |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728211/ https://www.ncbi.nlm.nih.gov/pubmed/34761267 http://dx.doi.org/10.1093/nar/gkab1006 |
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